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Inhibition of Centrosome Clustering Reduces Cystogenesis and Improves Kidney Function in Autosomal Dominant Polycystic Kidney Disease

Tao Cheng, Aruljothi Mariappan, Ewa Langner, et al.

Selected by Fiona Macleod

Alumni

Phosphoproteomics of cellular mechanosensing reveals NFATC4 as a regulator of myofibroblast activity

Laura F. Mattner, Zhen Zeng, Christoph H. Mayr, et al.

Selected by Rob Hynds

Pseudomonas aeruginosa contracts mucus to rapidly form biofilms in tissue-engineered human airways

Tamara Rossy, Tania Distler, Joern Pezoldt, et al.

Selected by Snehal Kadam

RNA targeting with CRISPR-Cas13a facilitates bacteriophage genome engineering

Jingwen Guan, Agnès Oromí-Bosch, Senén D. Mendoza, et al.

Selected by Mandy Neumann

Saturation variant interpretation using CRISPR prime editing

Steven Erwood, Teija M.I. Bily, Jason Lequyer, et al.

Selected by Jeffrey Calhoun

Three-axis classification of mouse lung mesenchymal cells reveals two populations of myofibroblasts

Odemaris Narvaez del Pilar, Jichao Chen

Selected by Sagar Varankar

TAZ/TEAD complex regulates TGF-β1-mediated fibrosis in iPSC-derived renal organoids

Xiaoping Yang, Marco Delsante, Parnaz Daneshpajouhnejad, et al.

Selected by Sagar Varankar

Resident Cardiac Macrophages Mediate Adaptive Myocardial Remodeling

Nicole R. Wong, Jay Mohan, Benjamin J Kopecky, et al.

Selected by Laura Alonso-Herranz

Antifungal effects of PC945, a novel inhaled triazole, on Candida albicans-infected immunocompromised mice

Yuki Nishimoto, Kazuhiro Ito, Genki Kimura, et al.

Selected by Zhang-He Goh

Intraperitoneal oil application causes local inflammation with depletion of resident peritoneal macrophages

Elisenda Alsina-Sanchis, Ronja Mülfarth, Iris Moll, et al.

Selected by Oindrila Bhattacharjee

Human skeletal muscle CD90⁺ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients

Jean Farup, Jesper Just, Frank de Paoli, et al.

Selected by Osvaldo Contreras, Nicolas Collao

Pharmacological Insights into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure

Patricia Rueda, Jon Merlin, Stefano Chimenti, et al.

Selected by Zhang-He Goh