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Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens

Emanuel Gonçalves, Aldo Segura-Cabrera, Clare Pacini, et al.

Selected by 20 March 2020

Georgina Sava

Cancer Biology

DRP1-mediated regulation of mitochondrial dynamics determines the apoptotic response upon embryonic differentiation

Barbara Pernaute, Juan Miguel Sánchez Nieto, Salvador Pérez-Montero, et al.

Selected by 12 February 2020

Katarzyna Kuzmicz-Kowalska

Developmental Biology

Differences in mitochondrial activity trigger cell competition during early mouse development

Ana Lima, Gabriele Lubatti, Jörg Burgstaller, et al.

Selected by 29 January 2020

Teresa Rayon

Developmental Biology

Akt/Foxo pathway activation switches apoptosis to senescence in short telomere zebrafish

Mounir El-Maï, Marta Marzullo, Inês Pimenta de Castro, et al.

Selected by 21 January 2020

Lorenzo Lafranchi

Cell Biology

Epigenetic gene silencing by heterochromatin primes fungal resistance

Sito Torres-Garcia, Pauline N. C. B. Audergon, Manu Shukla, et al.

Selected by 14 November 2019

Miguel V. Almeida

Genetics

Negative frequency-dependent selection maintains coexisting genotypes during fluctuating selection

Caroline B. Turner, Sean W. Buskirk, Katrina B. Harris, et al.

Selected by 18 September 2019

Defne Surujon

Evolutionary Biology

A modification to the life cycle of the parasite Trypanosoma brucei

Sarah Schuster, Ines Subota, Jaime Lisack, et al.

Selected by 13 August 2019

Mariana De Niz

Cell Biology

Gene regulatory network inference and analysis of multidrug-resistant Pseudomonas aeruginosa

Fernando Medeiros Filho, Ana Paula Barbosa do Nascimento, Marcelo Trindade dos Santos, et al.

Selected by 19 July 2019

Euan McDonnell

Bioinformatics

Active behaviour during early development shapes glucocorticoid reactivity

Luis A. Castillo-Ramírez, Soojin Ryu, Rodrigo J. De Marco

Selected by 05 April 2019

Kathleen Gilmour

Animal Behavior and Cognition

Acquired interbacterial defense systems protect against interspecies antagonism in the human gut microbiome

Benjamin D. Ross, Adrian J. Verster, Matthew C. Radey, et al.

Selected by 11 December 2018

Connor Rosen

Microbiology

Epiblast formation by Tead-Yap-dependent expression of pluripotency factors and competitive elimination of unspecified cells

Masakazu Hashimoto, Hiroshi Sasaki

Selected by 29 November 2018

Sarah Bowling, Teresa Rayon

Developmental Biology

The Toll pathway inhibits tissue growth and regulates cell fitness in an infection-dependent manner

Federico Germani, Daniel Hain, Denise Sternlicht, et al.

Selected by 24 November 2018

Rohan Khadilkar

Cell Biology