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Endogenous CRISPR arrays for scalable whole organism lineage tracing

James Cotterell, James Sharpe

Selected by 27 February 2019

Irepan Salvador-Martinez

Bioinformatics

Conditional Guide RNAs: Programmable Conditional Regulation of CRISPR/Cas Function in Bacteria via Dynamic RNA Nanotechnology

Mikhail H. Hanewich-Hollatz, Zhewei Chen, Jining Huang, et al.

Selected by 18 February 2019

Pavithran Ravindran

Bioengineering

Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells

Jayashree Chadchankar, Victoria Korboukh, Peter Doig, et al.

Selected by 31 January 2019

Mila Basic

Molecular Biology

Reconstruction of the global neural crest gene regulatory network in vivo

Ruth M Williams, Ivan Candido-Ferreira, Emmanouela Repapi, et al.

Selected by 28 January 2019

Hannah Brunsdon

Genomics

Phase transition and amyloid formation by a viral protein as an additional molecular mechanism of virus-induced cell toxicity

Edoardo Salladini, Claire Debarnot, Vincent Delauzun, et al.

Selected by 11 January 2019

Tessa Sinnige

Biophysics

A pharmacokinetic-pharmacodynamic assessment of the hepatic and bone-marrow toxicities of the new trypanoside fexinidazole

James Andrew Watson, Nathalie Strub-Wourgraft, Antoine Tarral, et al.

Selected by 18 December 2018

Zhang-He Goh

Pharmacology and Toxicology

Evidence for an Integrated gene Repression Mechanism based on mRNA Isoform Toggling in Human Cells

Ina Hollerer, Juliet C Barker, Victoria Jorgensen, et al.

Selected by 30 October 2018

Clarice Hong

Genetics

Target-specific precision of CRISPR-mediated genome editing

Anob M Chakrabarti, Tristan Henser-Brownhill, Josep Monserrat, et al.

Selected by 27 September 2018

Rob Hynds

Molecular Biology

CRISPR/Cas9-mediated gene deletion of the ompA gene in an Enterobacter gut symbiont impairs biofilm formation and reduces gut colonization of Aedes aegypti mosquitoes

Shivanand Hegde, Pornjarim Nilyanimit, Elena Kozlova, et al.

Selected by 21 September 2018

Snehal Kadam

Microbiology

Molecular recording of mammalian embryogenesis

Michelle Chan, Zachary D Smith, Stefanie Grosswendt, et al.

Selected by 23 August 2018

Hannah Brunsdon

LADL: Light-activated dynamic looping for endogenous gene expression control

Mayuri Rege, Ji Hun Kim, Jacqueline Valeri, et al.

Selected by 10 August 2018

Ivan Candido-Ferreira

Genomics

Functional testing of a human PBX3 variant in zebrafish reveals a potential modifier role in congenital heart defects

Gist H. Farr III, Kimia Imani, Darren Pouv, et al.

Selected by 03 July 2018

Hannah Brunsdon

Genetics