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Circadian Clock Programming of Anticipatory Antiviral Immunity Gates Enteric Virus Infection Susceptibility

Temitope O. Oshinowo, Robert W. Maples, Mikal A. Woods Acevedo, et al.

Inhibition of the gut ceramidase Asah2 decelerates the vertebrate ageing rate

Ayami Takaochi, Kota Abe, Yuki Sugiura, et al.

Discussion

Temporal degradation of PRC2 uncovers specific developmental dependencies

Ming-Kang Lee, Sebastian D. Mackowiak, Daniel Felismino, et al.

Gut microbiome changes over the course of multiple sclerosis differentially influence autoimmune neuroinflammation

Amélia Sarmento, Tommy Regen, Daniela Ferro, et al.

Discussion

Remote homology and functional genetics unmask deeply preserved Scm3/HJURP orthologs in metazoans

Jeremy A. Hollis, Jason A. Stonick, Irini Topalidou, et al.

Liquid-Liquid Phase Separation-mediated formation of amyloid fibrils from DcpS scavenger enzymes

Aleksandra Ferenc-Mrozek, Maria Winiewska-Szajewska, Hanna Nieznańska, et al.

Discussion

A thirty-year trend of increasing clinical orientation at the National Institutes of Health

Brad L. Busse, James M. Tucker, Summer E. Allen, et al.

AND

Prediction of transformative breakthroughs in biomedical research

Matthew T. Davis, Brad L. Busse, Salsabil Arabi, et al.

A drought stress-induced MYB transcription factor regulates pavement cell shape in leaves of European aspen (Populus tremula)

Sijia Liu, Siamsa M. Doyle, Kathryn M. Robinson, et al.

DNA Specimen Preservation using DESS and DNA Extraction in Museum Collections: A Case Study Report

Eri Ogiso-Tanaka, Daisuke Shimada, Akito Ogawa, et al.

PIP5K-Ras bistability triggers plasma membrane symmetry breaking to define cellular polarity and regulate migration

Yu Deng, Tatsat Banerjee, Satomi Matsuoka, et al.

Imaging cellular activity simultaneously across all organs of a vertebrate reveals body-wide circuits

Virginia M. S. Ruetten, Wei Zheng, Igor Siwanowicz, et al.

A high-coverage genome from a 200,000-year-old Denisovan

Stéphane Peyrégne, Diyendo Massilani, Yaniv Swiel, et al.

AND

A global map for introgressed structural variation and selection in humans

PingHsun Hsieh, Natthapon Soisangwan, David S. Gordon, et al.

Discussion