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A high-coverage genome from a 200,000-year-old Denisovan

Stéphane Peyrégne, Diyendo Massilani, Yaniv Swiel, et al.

AND

A global map for introgressed structural variation and selection in humans

PingHsun Hsieh, Natthapon Soisangwan, David S. Gordon, et al.

Discussion

In depth profiling of the cancer proteome from the flowthrough of standard RNA- preparation kits for precision oncology

Filip Mundt Madsen, Annelaura Bach Nielsen, Juanjuan Wang, et al.

TET knockout cells transit between pluripotent states and exhibit precocious germline entry

Raphaël Pantier, Elisa Barbieri, Sara Gonzalez Brito, et al.

Direct cell-to-cell transmission of retrotransposons

Maya Voichek, Andreas Bernhard, Maria Novatchkova, et al.

Discussion

A prophage-encoded anti-phage defense system that prevents phage DNA packaging by targeting the terminase complex

Gil Azulay, Nadejda Sigal, Keren Tzohar Rabinovich, et al.

Discussion

Early resident NK cell response to local HIV infection in lymphoid tissue

David Perea, Alba Gonzalez, Nerea Sanchez-Gaona, et al.

Discussion

IMMClock reveals immune aging and T cell function at single-cell resolution

Yael Gurevich Schmidt, Di Wu, Sanna Madan, et al.

Adenine DNA methylation associated to transcription is widespread across eukaryotes

Pedro Romero Charria, Cristina Navarrete, Vladimir Ovchinnikov, et al.

A fine kinetic balance of interactions directs transcription factor hubs to genes

Apratim Mukherjee, Samantha Fallacaro, Puttachai Ratchasanmuang, et al.

Modular control of time and space during vertebrate axis segmentation

Ali Seleit, Ian Brettell, Tomas Fitzgerald, et al.

AND

Natural genetic variation quantitatively regulates heart rate and dimension

Jakob Gierten, Bettina Welz, Tomas Fitzgerald, et al.

A revised single-cell transcriptomic atlas of Xenopus embryo reveals new differentiation dynamics

Kseniya Petrova, Maksym Tretiakov, Aleksandr Kotov, et al.

FoxO transcription factors actuate the formative pluripotency specific gene expression programme

Laura Santini, Saskia Kowald, Giovanni Sestini, et al.