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DNA Specimen Preservation using DESS and DNA Extraction in Museum Collections: A Case Study Report

Eri Ogiso-Tanaka, Daisuke Shimada, Akito Ogawa, et al.

A high-coverage genome from a 200,000-year-old Denisovan

Stéphane Peyrégne, Diyendo Massilani, Yaniv Swiel, et al.

AND

A global map for introgressed structural variation and selection in humans

PingHsun Hsieh, Natthapon Soisangwan, David S. Gordon, et al.

Discussion

In depth profiling of the cancer proteome from the flowthrough of standard RNA- preparation kits for precision oncology

Filip Mundt Madsen, Annelaura Bach Nielsen, Juanjuan Wang, et al.

Nucleoplasmic Lamin A/C controls replication fork restart upon stress by modulating local H3K9me3 and ADP-ribosylation levels

Veronica Cherdyntseva, Joanna Paulson, Selin Adakli, et al.

Discussion

Chromosomal instability in human trophoblast stem cells and placentas

Danyang Wang, Andrew Cearlock, Katherine Lane, et al.

Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair

Marieke R. Wensveen, Aditya A. Dixit, Serafin U. Colmenares, et al.

CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

Madison B. Adolph, Atharv S. Garje, Swati Balakrishnan, et al.

Discussion

Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis

Camille Gelot, Marton Tibor Kovacs, Simona Miron, et al.

Discussion

Inhibition of Centrosome Clustering Reduces Cystogenesis and Improves Kidney Function in Autosomal Dominant Polycystic Kidney Disease

Tao Cheng, Aruljothi Mariappan, Ewa Langner, et al.

Mitotic heritability of DNA methylation at intermediately methylated sites is imprecise

Amir D. Hay, Noah J. Kessler, Daniel Gebert, et al.

CTCF is essential for proper mitotic spindle structure and anaphase segregation

Katherine Chiu, Yasmin Berrada, Nebiyat Eskndir, et al.

Actin nucleators safeguard replication forks by limiting nascent strand degradation

Jadwiga Nieminuszczy, Peter R. Martin, Ronan Broderick, et al.

Discussion