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The hourglass model of evolutionary conservation during embryogenesis extends to developmental enhancers with signatures of positive selection

Jialin Liu, Rebecca R. Viales, Pierre Khoueiry, et al.

Selected by 11 December 2020

Irepan Salvador-Martinez

Bioinformatics

ARID1A regulates R-loop associated DNA replication stress

Shuhe Tsai, Emily Yun-Chia Chang, Louis-Alexandre Fournier, et al.

Selected by 05 December 2020

Sree Rama Chaitanya

Molecular Biology

SF3B1-targeted Splicing Inhibition Triggers Global Alterations in Transcriptional Dynamics and R-Loop Metabolism

Daisy Castillo-Guzman, Stella R. Hartono, Lionel A. Sanz, et al.

Selected by 06 November 2020

Sree Rama Chaitanya

Molecular Biology

Functional diversification of Ser-Arg rich protein kinases to control ubiquitin-dependent neurodevelopmental signalling

Francisco Bustos, Anna Segarra-Fas, Gino Nardocci, et al.

Selected by 22 September 2020

Sree Rama Chaitanya

Developmental Biology

Single-molecule live cell imaging of the Smc5/6 DNA repair complex

Thomas J. Etheridge, Desiree Villahermosa, Anja Irmisch, et al.

Selected by 26 June 2020

Jennifer Ann Black

Molecular Biology

Replication protein A binds RNA and promotes R-loop formation

Olga M. Mazina, Srinivas Somarowthu, Lyudmila Y. Kadyrova, et al.

Selected by 22 June 2020

Giuseppina D'Alessandro

Molecular Biology

Organoid Easytag: an efficient workflow for gene targeting in human organoids

Dawei Sun, Lewis D. Evans, Emma L. Rawlins

Selected by 22 May 2020

Kirsty Ferguson

Developmental Biology

Nuclear myosin VI regulates the spatial organization of mammalian transcription initiation

Yukti Hari-Gupta, Natalia Fili, Ália dos Santos, et al.

Selected by 05 May 2020

Jennifer Ann Black

Cell Biology

Constricted migration contributes to persistent 3D genome structure changes associated with an invasive phenotype in melanoma cells

Rosela Golloshi, Rebeca San Martin, Priyojit Das, et al.

Selected by 02 April 2020

Mariana De Niz

Cancer Biology

Species-specific developmental timing is associated with global differences in protein stability in mouse and human

Teresa Rayon, Despina Stamataki, Ruben Perez-Carrasco, et al.

Selected by 16 January 2020

Irepan Salvador-Martinez

Developmental Biology

Epigenetic gene silencing by heterochromatin primes fungal resistance

Sito Torres-Garcia, Pauline N. C. B. Audergon, Manu Shukla, et al.

Selected by 14 November 2019

Miguel V. Almeida

Genetics

Aging is associated with a systemic length-driven transcriptome imbalance

Thomas Stoeger, Rogan A. Grant, Alexandra C. McQuattie-Pimentel, et al.

Selected by 04 September 2019

Monika S. Magon

Systems Biology