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Combinatorial and Inducible CRISPRa/i Enables Canalized hiPSC Forward Programming and Iterative Refinement via Single-Cell genomics

Federica Sozza, Alberto Romano, Nicole D’Elia, et al.

Selected by 01 July 2026

Cell-ID

Synthetic Biology

Inhibition of the gut ceramidase Asah2 decelerates the vertebrate ageing rate

Ayami Takaochi, Kota Abe, Yuki Sugiura, et al.

Selected by 29 May 2026

Jeny Jose

Developmental Biology

DNA Specimen Preservation using DESS and DNA Extraction in Museum Collections: A Case Study Report

Eri Ogiso-Tanaka, Daisuke Shimada, Akito Ogawa, et al.

Selected by 17 February 2026

Daniel Fernando Reyes Enríquez, Marcus Oliveira

Zoology

Kosmos: An AI Scientist for Autonomous Discovery

Ludovico Mitchener, Angela Yiu, Benjamin Chang, et al.

Selected by 04 February 2026

Roberto Amadio et al.

Bioinformatics

A high-coverage genome from a 200,000-year-old Denisovan

Stéphane Peyrégne, Diyendo Massilani, Yaniv Swiel, et al.

AND

A global map for introgressed structural variation and selection in humans

PingHsun Hsieh, Natthapon Soisangwan, David S. Gordon, et al.

Selected by 02 December 2025

Siddharth Singh

Evolutionary Biology

Beyond venomous fangs: Uloboridae spiders have lost their venom but not their toxicity

Xiaojing Peng, Ludwig Dersch, Josephine Dresler, et al.

Selected by 13 November 2025

Daniel Fernando Reyes Enríquez, Marcus Oliveira

Evolutionary Biology

Environmental and Maternal Imprints on Infant Gut Metabolic Programming

Kine Eide Kvitne, Celeste Allaband, Jennifer C. Onuora, et al.

Selected by 26 October 2025

Siddharth Singh

Developmental Biology

STEAMBOAT: Attention-based multiscale delineation of cellular interactions in tissues

Shaoheng Liang, Junjie Tang, Guanghan Wang, et al.

Selected by 25 April 2025

Benjamin Dominik Maier

Bioinformatics

Early 2025 preprints – the genetics & genomics edition

In this community-driven preList, a group of preLighters, with expertise in different areas of genetics and genomics have worked together to create this preprint reading list. Categories include: 1) bioinformatics 2) epigenetics 3) gene regulation 4) genomics 5) transcriptomics

 



List by Chee Kiang Ewe et al.

End-of-year preprints – the genetics & genomics edition

In this community-driven preList, a group of preLighters, with expertise in different areas of genetics and genomics have worked together to create this preprint reading list. Categories include: 1) genomics 2) bioinformatics 3) gene regulation 4) epigenetics

 



List by Chee Kiang Ewe et al.

Autism gene variants disrupt enteric neuron migration and cause gastrointestinal dysmotility

Kate E. McCluskey, Katherine M. Stovell, Karen Law, et al.

Selected by 10 June 2024

Rachel Mckeown

Neuroscience

Enhancer cooperativity can compensate for loss of activity over large genomic distances

Henry Thomas, Songjie Feng, Marie Huber, et al.

Selected by 10 June 2024

Milan Antonovic

Genomics