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Single-cell epigenomic reconstruction of developmental trajectories in human neural organoid systems from pluripotency

Fides Zenk, Jonas Simon Fleck, Sophie Martina Johanna Jansen, et al.

Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair

Marieke R. Wensveen, Aditya A. Dixit, Serafin U. Colmenares, et al.

Sex-determining 3D regulatory hubs revealed by genome spatial auto-correlation analysis

Irene Mota-Gómez, Juan Antonio Rodríguez, Shannon Dupont, et al.

An epigenetic barrier sets the timing of human neuronal maturation

Gabriele Ciceri, Hyunwoo Cho, Meghana Kshirsagar, et al.

Diverse mechanisms for epigenetic imprinting in mammals

Daniel Andergassen, Zachary D. Smith, John L. Rinn, et al.

The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo

Giuliano Crispatzu, Rizwan Rehimi, Tomas Pachano, et al.

Orphan CpG islands boost the regulatory activity of poised enhancers and dictate the responsiveness of their target genes

Tomás Pachano, Víctor Sánchez-Gaya, María Mariner-Faulí, et al.

The deubiquitinase Usp9x regulates PRC2-mediated chromatin reprogramming during mouse development

Trisha A. Macrae, Miguel Ramalho-Santos

Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance

Ruben Schep, Eva Brinkman, Christ Leemans, et al.

Sister-chromatid-sensitive Hi-C reveals the conformation of replicated human chromosomes

Michael Mitter, Catherina Gasser, Zsuzsanna Takacs, et al.

Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics

S Basu, O Shukron, A Ponjavic, et al.

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Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy

Miles K. Huseyin, Robert J. Klose

KDM6B-dependent chromatin remodelling underpins effective virus-specific CD8⁺ T cell differentiation

Jasmine Li, Kristine Hardy, Moshe Olshansky, et al.