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Bromodomain Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV2 Infection in Pre-Clinical Models

Richard J Mills, Sean J Humphrey, Patrick RJ Fortuna, et al.

Selected by 27 November 2020

Alexander Ward, Osvaldo Contreras

Bioengineering

Deep learning-enhanced light-field imaging with continuous validation

Nils Wagner, Fynn Beuttenmueller, Nils Norlin, et al.

Selected by 04 November 2020

Mariana De Niz

Bioengineering

Heterogeneity in collective endothelial cell behavior is a driver of arterio-venous remodeling

Keyi Jiang, Cathy Pichol-Thievend, Zoltan Neufeld, et al.

Selected by 02 October 2020

Jessica L. Teo

Cell Biology

Pharmacological Insights into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of heart Failure

Patricia Rueda, Jon Merlin, Stefano Chimenti, et al.

Selected by 08 September 2020

Zhang-He Goh

Pharmacology and Toxicology

Hydration-dependent phase separation of a prion-like protein regulates seed germination during water stress

Yanniv Dorone, Steven Boeynaems, Benjamin Jin, et al.

Selected by 28 August 2020

Martin Balcerowicz

Plant Biology

Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart

Thomas J. Cahill, Xin Sun, Christophe Ravaud, et al.

Selected by 25 August 2020

Jonny Coates

Developmental Biology

A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic heart Disease

Michael Alexanian, Pawel F. Przytycki, Rudi Micheletti, et al.

Selected by 11 August 2020

Osvaldo Contreras, Alexander Ward

Cell Biology

Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity

Ghazal Babolmorad, Asna Latif, Niall M. Pollock, et al.

AND

Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity

Francisco Inesta-Vaquera, Panida Navasumrit, Colin J. Henderson, et al.

Selected by 07 August 2020

Zhang-He Goh

Pharmacology and Toxicology

Apico-basal cell compression regulates Lamin A/C levels in Epithelial tissues

K Venkatesan Iyer, Natalie A. Dye, Suzanne Eaton, et al.

Selected by 05 August 2020

Ilaria Di Meglio

Biophysics

Cardioids reveal self-organizing principles of human cardiogenesis

Pablo Hofbauer, Stefan Jahnel, Nora Papai, et al.

Selected by 20 July 2020

Alok Javali

Developmental Biology

Neural plate targeting by in utero nanoinjection (NEPTUNE) reveals a role for Sptbn2 in neurulation and abdominal wall closure

Katrin Mangold, Jan Mašek, Jingyan He, et al.

Selected by 24 June 2020

Martin Estermann

Neuroscience

Astrocytes close a critical period of motor circuit plasticity

Sarah D. Ackerman, Nelson A. Perez-Catalan, Marc R. Freeman, et al.

Selected by 09 June 2020

Sejal Davla

Neuroscience