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A high-coverage genome from a 200,000-year-old Denisovan

Stéphane Peyrégne, Diyendo Massilani, Yaniv Swiel, et al.

AND

A global map for introgressed structural variation and selection in humans

PingHsun Hsieh, Natthapon Soisangwan, David S. Gordon, et al.

Discussion

Spurring and Siloing: Identity Navigation in Scientific Writing Among Asian Early-Career Researchers

Devon Goss, Shaila Sachdev, Grace Kim, et al.

Tooth development in frogs: Implications for the re-evolution of lost mandibular teeth and the origin of a morphological innovation

Daniel J. Paluh, Madeline Brinkman, Kyliah Gilliam-Beale, et al.

Enzymatic access to the rare ΔUA (1→4) Glc 3, 6, N-sulfated heparin disaccharide, implications for heparin quality control

T. K. Kandola, C. J. Mycroft-West, M. L. Andrade De Lima, et al.

Discussion

Cellular signalling protrusions enable dynamic distant contacts in spinal cord neurogenesis

Joshua Hawley, Robert Lea, Veronica Biga, et al.

Adult caudal fin shape is imprinted in the embryonic fin fold

Eric Surette, Joan Donahue, Stephanie Robinson, et al.

Triglyceride metabolism controls inflammation and APOE4-associated disease states in microglia

Roxan A. Stephenson, Kory R. Johnson, Linling Cheng, et al.

TAK1 operates at the primary cilium in non-canonical TGFB/BMP signaling to control heart development

Canan Doganli, Daniel A. Baird, Yeasmeen Ali, et al.

A choroid plexus apocrine secretion mechanism shapes CSF proteome and embryonic brain development

Ya’el Courtney, Joshua P. Head, Elizabeth D. Yimer, et al.

Discussion

FoxO transcription factors actuate the formative pluripotency specific gene expression programme

Laura Santini, Saskia Kowald, Giovanni Sestini, et al.

Generating human neural diversity with a multiplexed morphogen screen in organoids

Neal D. Amin, Kevin W. Kelley, Jin Hao, et al.

Cell polarity linked to gravity sensing is generated by protein translocation from statoliths to the plasma membrane

Takeshi Nishimura, Shogo Mori, Hiromasa Shikata, et al.

AND

Amyloplast sedimentation repolarizes LAZYs to achieve gravity sensing in plants

Jiayue Chen, Renbo Yu, Na Li, et al.