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RNA targeting with CRISPR-Cas13a facilitates bacteriophage genome engineering

Jingwen Guan, Agnès Oromí-Bosch, Senén D. Mendoza, et al.

Selected by 23 April 2022

Mandy Neumann

Microbiology

Drag-and-drop genome insertion without DNA cleavage with CRISPR-directed integrases

Eleonora I. Ioannidi, Matthew T. N. Yarnall, Cian Schmitt-Ulms, et al.

Selected by 15 December 2021

Louise Moyle et al.

Genomics

Two redundant ubiquitin-dependent pathways of BRCA1 localization to DNA damage sites

Alana Sherker, Natasha Chaudhary, Salomé Adam, et al.

Selected by 10 August 2021

Giuseppina D'Alessandro

Cell Biology

Scaling of cellular proteome with ploidy

Galal Yaha, Paul Menges, Devi Anggraini Ngandiri, et al.

Selected by 31 May 2021

Jennifer Ann Black

Cell Biology

Repurposing of Synaptonemal Complex Proteins for Kinetochores in Kinetoplastida

Eelco C. Tromer, Thomas A. Wemyss, Ross F. Waller, et al.

Selected by 17 May 2021

Hiral Shah, Dey Lab

Evolutionary Biology

Host defense mechanisms induce genome instability in an opportunistic fungal pathogen

Amanda Smith, Meleah A. Hickman

Selected by 30 April 2021

Jennifer Ann Black

Genomics

EccDNA formation is dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA double-strand break

Teressa Paulsen, Pumoli Malapati, Rebeka Eki, et al.

Selected by 05 January 2021

Sree Rama Chaitanya

Cancer Biology

ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination deficient cells

Priyanka Verma, Yeqiao Zhou, Zhendong Cao, et al.

Selected by 31 December 2020

Giuseppina D'Alessandro

Cancer Biology

Intercellular telomere transfer extends T cell lifespan

Bruno Vaz, Claudia Vuotto, Salvatore Valvo, et al.

Selected by 23 October 2020

Giuseppina D'Alessandro

Immunology

Aberrant replication licensing drives Copy Number Gains across species

Patroula Nathanailidou, Michalis Petropoulos, Styliani Maxouri, et al.

Selected by 12 October 2020

Yasmin Lau

Genetics

Severe immunodeficiency in mice lacking DNA repair factors XLF and Mri

Sergio Castañeda-Zegarra, Qindong Zhang, Amin Alirezaylavasani, et al.

Selected by 27 July 2020

Jennifer Ann Black

Immunology

Single-molecule live cell imaging of the Smc5/6 DNA repair complex

Thomas J. Etheridge, Desiree Villahermosa, Anja Irmisch, et al.

Selected by 26 June 2020

Jennifer Ann Black

Molecular Biology