Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair
Selected by
15 December 2023
Pierre Caron

The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity
Selected by
14 November 2023
Audrey Noireterre

Tardigrades dramatically upregulate DNA repair pathway genes in response to ionizing radiation
Selected by
18 October 2023
Isabella Cisneros

CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity
Selected by
06 September 2023
Jessica Chevallier, Pierre Caron

Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis
Selected by
05 June 2023
Pierre Caron

EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells
Selected by
15 May 2023
Jennifer Ann Black

Massively parallel protein-protein interaction measurement by sequencing (MP3-seq) enables rapid screening of protein heterodimers
Selected by
07 April 2023
Benjamin Dominik Maier

BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote replication fork stability and continuous DNA synthesis
Selected by
09 March 2023
Pierre Caron

Nuclear myosin VI maintains replication fork stability
Selected by
13 December 2022
Pierre Caron

Key roles for kinesin-13 and kinesin-20 in malaria parasite proliferation, polarity and transmission revealed by genome-wide functional analysis
Selected by
19 May 2022
Jessica Kehrer

RNA targeting with CRISPR-Cas13a facilitates bacteriophage genome engineering
Selected by
23 April 2022
Mandy Neumann

Drag-and-drop genome insertion without DNA cleavage with CRISPR-directed integrases
Selected by
15 December 2021
Louise Moyle et al.
