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EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells

B. van de Kooij, A. Schreuder, R.S. Pavani, et al.

Selected by 15 May 2023

Jennifer Ann Black

Molecular Biology

Therapeutic strategy for spinal muscular atrophy by combining gene supplementation and genome editing

Fumiyuki Hatanaka, Keiichiro Suzuki, Kensaku Shojima, et al.

Selected by 03 May 2023

Preethi Krishnaraj

Neuroscience

ATM-dependent formation of a novel chromatin compartment regulates the Response to DNA Double Strand Breaks and the biogenesis of translocations

Coline Arnould, Vincent Rocher, Aldo S. Bader, et al.

Selected by 17 February 2022

Jennifer Ann Black

Molecular Biology

Drag-and-drop genome insertion without DNA cleavage with CRISPR-directed integrases

Eleonora I. Ioannidi, Matthew T. N. Yarnall, Cian Schmitt-Ulms, et al.

Selected by 15 December 2021

Louise Moyle et al.

Genomics

Saturation variant interpretation using CRISPR prime editing

Steven Erwood, Teija M.I. Bily, Jason Lequyer, et al.

Selected by 20 October 2021

Jeffrey Calhoun

Genetics

Organoid Easytag: an efficient workflow for gene targeting in human organoids

Dawei Sun, Lewis D. Evans, Emma L. Rawlins

Selected by 22 May 2020

Kirsty Ferguson

Developmental Biology

The histone chaperone FACT induces Cas9 multi-turnover behavior and modifies genome manipulation in human cells

Alan S. Wang, Leo Chen, R. Alex Wu, et al.

Selected by 20 August 2019

Nicola Stevenson

Molecular Biology

Super-Mendelian inheritance mediated by CRISPR/Cas9 in the female mouse germline

Hannah A. Grunwald, Valentino M. Gantz, Gunnar Poplawski, et al.

Selected by 16 July 2018

Rebekah Tillotson

Synthetic Biology

Functional testing of a human PBX3 variant in zebrafish reveals a potential modifier role in congenital heart defects

Gist H. Farr III, Kimia Imani, Darren Pouv, et al.

Selected by 03 July 2018

Hannah Brunsdon

Genetics