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Simultaneous multiplexed amplicon sequencing and transcriptome profiling in single cells

Mridusmita Saikia, Philip Burnham, Sara H Keshavjee, et al.

AND

High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes

Mandeep Singh, Ghamdan Al-Eryani, Shaun Carswell, et al.

Discussion

Molecular organization of integrin-based adhesion complexes in mouse Embryonic Stem Cells

Shumin Xia, Evelyn K.F. Yim, Pakorn Kanchanawong

AND

Superresolution architecture of pluripotency guarding adhesions

Aki Stubb, Camilo Guzmán, Elisa Närvä, et al.

Discussion

Evidence for an Integrated Gene Repression Mechanism based on mRNA Isoform Toggling in human Cells

Ina Hollerer, Juliet C Barker, Victoria Jorgensen, et al.

Discussion

Revealing the nanoscale morphology of the primary cilium using super-resolution fluorescence microscopy

Joshua Yoon, Colin J. Comerci, Lucien E. Weiss, et al.

Discussion

Synergy with TGFβ ligands switches WNT pathway dynamics from transient to sustained during human pluripotent cell differentiation

Joseph Massey, Yida Liu, Omar Alvarenga, et al.

LCM-seq reveals unique transcriptional adaption mechanisms of resistant neurons in spinal muscular atrophy

Susanne Nichterwitz, Helena Storvall, Jik Nijssen, et al.

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Axon-seq decodes the motor axon transcriptome and its modulation in response to ALS

Jik Nijssen, Julio Cesar Aguila Benitez, Rein Hoogstraaten, et al.

Discussion

mRNA localisation in endothelial cells regulates blood vessel sprouting

Guilherme Costa, Nawseen Tarannum, Shane Herbert

Discussion

A transition from SoxB1 to SoxE transcription factors is essential for progression from pluripotent blastula cells to neural crest cells

Elsy Buitrago-Delgado, Elizabeth Schock, Kara Nordin, et al.

Discussion

Phenotypic landscape of schizophrenia-associated genes defines candidates and their shared functions

Summer B. Thyme, Lindsey M. Pieper, Eric H. Li, et al.

Discussion

Super-Mendelian inheritance mediated by CRISPR/Cas9 in the female mouse germline

Hannah A. Grunwald, Valentino M. Gantz, Gunnar Poplawski, et al.

TORC1 modulation in adipose tissue is required for organismal adaptation to hypoxia in Drosophila.

Byoungchun Lee, Elizabeth C Barretto, Savraj S Grewal

Discussion

Functional testing of a human PBX3 variant in zebrafish reveals a potential modifier role in congenital heart defects

Gist H. Farr III, Kimia Imani, Darren Pouv, et al.

Discussion