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Telomeric antisense oligonucleotides reduce premature aging phenotypes in telomerase mutant zebrafish

Giulia Allavena, Francesca Rossiello, Aurora Irene Idilli, et al.

Mechanical fracturing of the extracellular matrix patterns the vertebrate heart

Christopher Chan Jin Jie, Daniel Santos-Oliván, Marie-Christine Ramel, et al.

HIF1A contributes to the survival of aneuploid and mosaic pre-implantation embryos

Estefania Sanchez-Vasquez, Marianne E. Bronner, Magdalena Zernicka-Goetz

Lineage-specific CDK activity dynamics characterize early mammalian development

Bechara Saykali, Andy D. Tran, James A. Cornwell, et al.

Gestational exposure to high heat-humidity conditions impairs mouse embryonic development

Avinchal Manhas, Amritesh Sarkar, Srimonta Gayen

Discussion

Modular control of time and space during vertebrate axis segmentation

Ali Seleit, Ian Brettell, Tomas Fitzgerald, et al.

AND

Natural genetic variation quantitatively regulates heart rate and dimension

Jakob Gierten, Bettina Welz, Tomas Fitzgerald, et al.

Autism gene variants disrupt enteric neuron migration and cause gastrointestinal dysmotility

Kate E. McCluskey, Katherine M. Stovell, Karen Law, et al.

Notch3 is a genetic modifier of NODAL signalling for patterning asymmetry during mouse heart looping

Tobias Holm Bønnelykke, Marie-Amandine Chabry, Emeline Perthame, et al.

Discussion

Actin polymerization drives lumen formation in a human epiblast model

Dhiraj Indana, Andrei Zakharov, Youngbin Lim, et al.

A revised single-cell transcriptomic atlas of Xenopus embryo reveals new differentiation dynamics

Kseniya Petrova, Maksym Tretiakov, Aleksandr Kotov, et al.

Single-cell epigenomic reconstruction of developmental trajectories in human neural organoid systems from pluripotency

Fides Zenk, Jonas Simon Fleck, Sophie Martina Johanna Jansen, et al.

Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery

Jayne Aiken, Erika L. F. Holzbaur

Discussion