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A thirty-year trend of increasing clinical orientation at the National Institutes of Health

Brad L. Busse, James M. Tucker, Summer E. Allen, et al.

AND

Prediction of transformative breakthroughs in biomedical research

Matthew T. Davis, Brad L. Busse, Salsabil Arabi, et al.

A drought stress-induced MYB transcription factor regulates pavement cell shape in leaves of European aspen (Populus tremula)

Sijia Liu, Siamsa M. Doyle, Kathryn M. Robinson, et al.

PPARδ activation in microglia drives a transcriptional response that primes phagocytic function while countering inflammatory activation

Jacob S. Deyell, Jonathan Hasselmann, Linda Stroud, et al.

Discussion

The lipidomic architecture of the mouse brain

Luca Fusar Bassini, Halima Hannah Schede, Laura Capolupo, et al.

Discussion

A Novel Chimeric Antigen Receptor (CAR) - Strategy to Target EGFRVIII-Mutated Glioblastoma Cells via Macrophages

Kristi Vera, Gülen Esken, Jin Wook Hwang, et al.

Discussion

Cryo-EM reveals multiple mechanisms of ribosome inhibition by doxycycline

William S. Stuart, Michail N. Isupov, Mathew McLaren, et al.

A high-coverage genome from a 200,000-year-old Denisovan

Stéphane Peyrégne, Diyendo Massilani, Yaniv Swiel, et al.

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A global map for introgressed structural variation and selection in humans

PingHsun Hsieh, Natthapon Soisangwan, David S. Gordon, et al.

Post-translational Tuning of Human Cortical Progenitor Neuronal Output

Julien Pigeon, Tamina Dietl, Myriame Abou Mrad, et al.

Gut microbial composition modulates food-specific CD4⁺ T cells in food allergy

Alexa R Weingarden, Flannery S Dahlberg, Caroline N Broude, et al.

ROCK2 inhibition has a dual role in reducing ECM remodelling and cell growth, while impairing migration and invasion

Daniel A. Reed, Anna E. Howell, Nadia Kuepper, et al.

Dissecting Gene Regulatory Networks Governing Human Cortical Cell Fate

Jingwen W. Ding, Chang N. Kim, Megan S. Ostrowski, et al.

Human single-cell atlas analysis reveals heterogeneous endothelial signaling

Zimo Zhu, Rongbin Zheng, Yang Yu, et al.

Discussion