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Cytoskeletal tension actively sustains the migratory T cell synaptic contact

Sudha Kumari, Michael Mak, Yehchuin Poh, et al.

Selected by 11 June 2019

Tim Fessenden

Immunology

Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies

Candice Gurbatri, Courtney Coker, Taylor E. Hinchliffe, et al.

AND

Programmable bacteria induce durable tumor regression and systemic antitumor immunity

Sreyan Chowdhury, Taylor E Hinchliffe, Samuel Castro, et al.

Selected by 09 May 2019

Pavithran Ravindran

Bioengineering

Tousled-like kinase activity is required for transcriptional silencing and suppression of innate immune signaling

Sandra Segura-Bayona, Marina Villamor-Payà, Camille Stephan-Otto Attolini, et al.

Selected by 06 May 2019

Yasmin Lau

Molecular Biology

3D microenvironment stiffness regulates tumor spheroid growth and mechanics via p21 and ROCK

Anna V. Taubenberger, Salvatore Girardo, Nicole Träber, et al.

Selected by 03 May 2019

Jacky G. Goetz

Cancer Biology

Transcriptome analysis of Plasmodium berghei during exo-erythrocytic development

Reto Caldelari, Sunil Dogga, Marc W. Schmid, et al.

Selected by 02 May 2019

Mariana De Niz

Bioinformatics

Slide-seq: A Scalable Technology for Measuring Genome-Wide Expression at High Spatial Resolution

Samuel G Rodriques, Robert R Stickels, Aleksandrina Goeva, et al.

AND

High-density spatial transcriptomics arrays for in situ tissue profiling

Sanja Vickovic, Goekcen Eraslan, Johanna Klughammer, et al.

Selected by 20 March 2019

Carmen Adriaens

Bioinformatics

Myc instructs and maintains pancreatic adenocarcinoma phenotype

Nicole M Sodir, Roderik M Kortlever, Valentin JA Barthet, et al.

Selected by 08 March 2019

William Hill

Cancer Biology

MicroRNA-mediated control of developmental lymphangiogenesis

Hyun Min Jung, Ciara Hu, Alexandra M Fister, et al.

Selected by 07 March 2019

Rudra Nayan Das

Developmental Biology

CXCR3-expressing metastasis-initiating cells induce and exploit a fibroblast niche in the lungs to fuel metastatic colonization

Maren Pein, Jacob Insua-Rodriguez, Jasmin Meier, et al.

Selected by 05 March 2019

Julija Hmeljak

Prospective, brain-wide labeling of neuronal subclasses with enhancer-driven AAVs

Lucas T Graybuck, Adriana Sedeño-Cortés, Thuc Nghi Nguyen, et al.

Selected by 27 February 2019

Jesus Victorino

Neuroscience

SLC19A1 is a cyclic dinucleotide transporter

Rutger Luteijn, Shivam Zaver, Benjamin G Gowen, et al.

AND

SLC19A1 is an importer of the immunotransmitter cGAMP

Anthony F. Cordova, Christopher Ritchie, Gaelen T. Hess, et al.

AND

2'3'-cGAMP is an immunotransmitter produced by cancer cells and regulated by ENPP1

Jacqueline A Carozza, Volker Boehnert, Kelsey E Shaw, et al.

Selected by 13 February 2019

Connor Rosen

Immunology

Quantification of microenvironmental metabolites in murine cancer models reveals determinants of tumor nutrient availability

Mark R Sullivan, Laura V Danai, Caroline A Lewis, et al.

Selected by 11 February 2019

Maria Rafaeva

Cancer Biology