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SLC19A1 is a cyclic dinucleotide transporter

Rutger Luteijn, Shivam Zaver, Benjamin G Gowen, et al.

AND

SLC19A1 is an importer of the immunotransmitter cGAMP

Anthony F. Cordova, Christopher Ritchie, Gaelen T. Hess, et al.

AND

2'3'-cGAMP is an immunotransmitter produced by cancer cells and regulated by ENPP1

Jacqueline A Carozza, Volker Boehnert, Kelsey E Shaw, et al.

Selected by 13 February 2019

Connor Rosen

Immunology

Quantification of microenvironmental metabolites in murine cancer models reveals determinants of tumor nutrient availability

Mark R Sullivan, Laura V Danai, Caroline A Lewis, et al.

Selected by 11 February 2019

Maria Rafaeva

Cancer Biology

A conserved MFS orchestrates a subset of O-glycosylation to facilitate macrophage dissemination and tissue invasion

Katarina Valoskova, Julia Biebl, Marko Roblek, et al.

Selected by 23 January 2019

Giuliana Clemente

Cancer Biology

Biofilm/Persister/Stationary Phase Bacteria Cause More Severe Disease Than Log Phase Bacteria II Infection with Persister Forms of Staphylococcus aureus Causes a Chronic Persistent Skin Infection with More Severe Lesion that Takes Longer to Heal and is not Eradicated by the Current Recommended Treatment in Mice

Rebecca Yee, Yuting Yuan, Cory Brayton, et al.

Selected by 20 December 2018

Snehal Kadam

Microbiology

The Toll pathway inhibits tissue growth and regulates cell fitness in an infection-dependent manner

Federico Germani, Daniel Hain, Denise Sternlicht, et al.

Selected by 24 November 2018

Rohan Khadilkar

Cell Biology

The landscape of antigen-specific T cells in human cancers

Bo Li, Longchao Liu, Jian Zhang, et al.

Selected by 19 November 2018

Rob Hynds

Cancer Biology

Single-cell RNA sequencing reveals novel cell differentiation dynamics during human airway epithelium regeneration

Sandra Ruiz Garcia, Marie Deprez, Kevin Lebrigand, et al.

Selected by 10 November 2018

Rob Hynds

Cell Biology

Target-specific precision of CRISPR-mediated genome editing

Anob M Chakrabarti, Tristan Henser-Brownhill, Josep Monserrat, et al.

Selected by 27 September 2018

Rob Hynds

Molecular Biology

Damage-induced reactive oxygen species enable zebrafish tail regeneration by repositioning of Hedgehog expressing cells.

Henry Roehl, Montserrat Garcia Romero, Gareth McCathie, et al.

Selected by 25 September 2018

Alberto Rosello-Diez

Developmental Biology

PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection

Catherine M Buckley, Victoria L Heath, Aurelie Gueho, et al.

Selected by 13 September 2018

Giuliana Clemente

Cell Biology

Precise tuning of gene expression output levels in mammalian cells

Yale S. Michaels, Mike B Barnkob, Hector Barbosa, et al.

Selected by 08 August 2018

Tim Fessenden

Genomics

Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages is necessary for functional spinal cord regeneration in zebrafish

Themistoklis M. Tsarouchas, Daniel Wehner, Leonardo Cavone, et al.

Selected by 30 July 2018

Shikha Nayar

Developmental Biology