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Guide RNA categorization enables target site choice in Tn7-CRISPR-Cas transposons

Michael T. Petassi, Shan-Chi Hsieh, Joseph E. Peters

PINK1 and parkin shape the organism-wide distribution of a deleterious mitochondrial genome

Arnaud Ahier, Nadia Cummins, Chuan-Yang Dai, et al.

Insights into the salivary N-glycome of Lutzomyia longipalpis, vector of visceral leishmaniasis

Karina Mondragon-Shem, Katherine Wongtrakul-Kish, Radoslaw P. Kozak, et al.

Allergen-induced dendritic cell migration is controlled through Substance P release by sensory neurons

Pamela A. Aderhold, Zaynah N. A. Dewan, Caroline Perner, et al.

Discussion

Antibody repertoire and gene expression dynamics of diverse human B cell states during affinity maturation

Hamish W King, Nara Orban, John C Riches, et al.

Discussion

Dectin-1 limits central nervous system autoimmunity through a non-canonical pathway

M. Elizabeth Deerhake, Keiko Danzaki, Makoto Inoue, et al.

Discussion

Gain of gene regulatory network interconnectivity at the origin of vertebrates

Alejandro Gil-Gálvez, Sandra Jiménez-Gancedo, Rafael D. Acemel, et al.

Immune factor of bacterial origin protects ticks against host microbial commensals

Beth M. Hayes, Atanas D. Radkov, Fauna Yarza, et al.

Discussion

Mutual Potentiation of Plant immunity by Cell-surface and Intracellular Receptors

Bruno Pok Man Ngou, Hee-Kyung Ahn, Pingtao Ding, et al.

AND

Pattern-recognition receptors are required for NLR-mediated plant immunity

Minhang Yuan, Zeyu Jiang, Guozhi Bi, et al.

Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance

Anne Ramsay Bowden, David A. Morales Juarez, Matylda Sczaniecka-Clift, et al.

Conflicts with diarrheal pathogens trigger rapid evolution of an intestinal signaling axis

Clayton M. Carey, Sarah E. Apple, Zoё A. Hilbert, et al.

A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity

Elaine Thai, Giulia Costa, Anna Weyrich, et al.

Discussion