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Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen

Aravind Madhavan, K B Arun, Akhil Raj Pushparajan, et al.

AND

Tamoxifen reduces inflammatory infiltration of neutrophils in the airways

Agustín Mansilla, Jaime Soto, Claudio Henríquez, et al.

Discussion

A lung-on-chip model reveals an essential role for alveolar epithelial cells in controlling bacterial growth during early tuberculosis

Vivek V. Thacker, Neeraj Dhar, Kunal Sharma, et al.

LFA-1 signals to promote actin polymerization and upstream migration in T cells

Nathan H Roy, Sarah Hyun Ji Kim, Alexander Buffone Jr, et al.

A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity

Elaine Thai, Giulia Costa, Anna Weyrich, et al.

Discussion

Origin and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages

Calum C. Bain, Douglas A. Gibson, Nicholas Steers, et al.

Discussion

Polypyrimidine Tract Binding Proteins are essential for B cell development

Elisa Monzón-Casanova, Louise S. Matheson, Kristina Tabbada, et al.

Discussion

Brucella effector hijacks endoplasmic reticulum quality control machinery to prevent premature egress

Jean-Baptiste Luizet, Julie Raymond, Thais Lourdes Santos Lacerda, et al.

Discussion

Integrated Metabolomic and Transcriptomic Profiling Reveals Novel Activation-Induced Metabolic Networks in Human T cells

S. Hiemer, S. Jatav, J. Jussif, et al.

Discussion

Cytoskeletal tension actively sustains the migratory T cell synaptic contact

Sudha Kumari, Michael Mak, Yehchuin Poh, et al.

Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies

Candice Gurbatri, Courtney Coker, Taylor E. Hinchliffe, et al.

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Programmable bacteria induce durable tumor regression and systemic antitumor immunity

Sreyan Chowdhury, Taylor E Hinchliffe, Samuel Castro, et al.

Discussion

MicroRNA-mediated control of developmental lymphangiogenesis

Hyun Min Jung, Ciara Hu, Alexandra M Fister, et al.

Discussion