Search results

Combinatorial and inducible CRISPRa/i Enables Canalized hiPSC Forward Programming and Iterative Refinement via Single-Cell Genomics

Federica Sozza, Alberto Romano, Nicole D’Elia, et al.

Selected by 01 July 2026

Cell-ID

Deep invaginations of Nuclear Envelope Coordinate Spatial Organization of Chromatin in Epithelium

Elina Mäntylä, Sanna Korpela, Anna Rekonen, et al.

Selected by 02 June 2026

Abby Hein

Discussion

Chromatin priming and co-factor availability shape lineage response to the neuronal pioneer factor ASCL1 in pluripotency

Jethro Lundie-Brown, Rosalind Drummond, John-Poul Ng-Blichfeldt, et al.

Selected by 21 May 2026

Reinier Prosee, Jethro Lundie-Brown

Scalable transcription factor mapping uncovers the regulatory dynamics of natural and synthetic transcription factors in human T cell states

Riley D.Z. Mullins, Jesse Zaretsky, Emily Stoller, et al.

Selected by 09 December 2025

inês Caiado

Discussion

Post-translational Tuning of Human Cortical Progenitor Neuronal Output

Julien Pigeon, Tamina Dietl, Myriame Abou Mrad, et al.

Selected by 01 December 2025

Jawdat Sandakly

Aspartate transaminases are required for blood development

Narges Pourmandi, Greggory Myers, Arjun Jha, et al.

Selected by 26 November 2025

Hannah Pletcher

Matrix viscoelasticity regulates dendritic cell migration and immune priming

Wei-Hung Jung, Emie Humann, Joshua M Price, et al.

Selected by 03 November 2025

Roberto Amadio

High-throughput single-cell CRISPRi screens stratify neurodevelopmental functions of schizophrenia-associated genes

Umut Yildiz, Annique Claringbould, Mikael Marttinen, et al.

Selected by 27 October 2025

Manuel Lessi, Riccardo Nagni

Discussion

Human pluripotent stem cell-derived atrioventricular node-like pacemaker cells exhibit biological conduction bridge properties in vitro and in vivo

Michelle Lohbihler, Amos A. Lim, Stéphane Massé, et al.

Selected by 27 October 2025

Theodora Stougiannou

Fibro-Adipogenic Progenitors require autocrine IGF-I in homeostatic and regenerating skeletal muscle

Yangyi E. Luo, Zoe Abe-Teh, Tarek Y. Alsaghir, et al.

Selected by 24 October 2025

Hafsa Zahid

Discussion

Temporal single-cell sequencing analysis reveals that GPNMB-expressing macrophages potentiate muscle regeneration

Yu-Fan Chen, Chien-Wei Lee, Yi-Shuan J.Li, et al.

Selected by 19 October 2025

Hafsa Zahid

Tumor-infiltrating CD27^-IgD^- regulatory B cells suppress cytotoxic CD8⁺T cell responses in renal cell carcinoma

Zara Baig, Isabella Withnell, Joseph C.F. Ng, et al.

Selected by 12 August 2025

Charis Qi