Search results

Dual inhibition of GTP-bound (ON) and GDP-bound (OFF) KRAS^G12C suppresses PI3Kα and leads to potent tumor inhibition

Katherine Parker, Samar Ghorbanpoor, Wafa Malik, et al.

Selected by 03 June 2026

Luis Luna Ramírez

Discussion

Deep invaginations of Nuclear Envelope Coordinate Spatial Organization of Chromatin in Epithelium

Elina Mäntylä, Sanna Korpela, Anna Rekonen, et al.

Selected by 02 June 2026

Abby Hein

Discussion

Chromatin priming and co-factor availability shape lineage response to the neuronal pioneer factor ASCL1 in pluripotency

Jethro Lundie-Brown, Rosalind Drummond, John-Poul Ng-Blichfeldt, et al.

Selected by 21 May 2026

Reinier Prosee, Jethro Lundie-Brown

Temporal degradation of PRC2 uncovers specific developmental dependencies

Ming-Kang Lee, Sebastian D. Mackowiak, Daniel Felismino, et al.

Selected by 19 May 2026

María Mariner-Faulí

The metabolome and proteome of stem cell-derived human primordial germ cells: a multi-omics approach

Madalena Vaz Santos, Bauke V. Schomakers, Llobet Ayala Marta, et al.

Selected by 19 May 2026

Alan Leung

Liquid-Liquid Phase Separation-mediated formation of amyloid fibrils from DcpS scavenger enzymes

Aleksandra Ferenc-Mrozek, Maria Winiewska-Szajewska, Hanna Nieznańska, et al.

Selected by 06 April 2026

Joao Gabriel, Marcus Oliveira

4,5-dihydroxyhexanoic acid is a robust circulating and urine marker of mitochondrial disease and its severity

Owen S. Skinner, Maria Miranda, Fangcong Dong, et al.

Selected by 01 April 2026

Hannah Pletcher

Discussion

Human Assembloid Model of Emergent Neurotropic Enteroviruses

Christine E. Peters, Jimena Andersen, Min-Yin Li, et al.

Selected by 01 April 2026

Mitchell Sarmie

Discussion

Detergent-Triggered Membrane Remodelling Monitored via intramembrane Fluorescence De-Quenching

Claudia M. F. Andrews, Christopher M. Hofmair, Lauryn Roberts, et al.

Selected by 25 March 2026

Cyntia Alves Conceição, Marcus Oliveira

Discussion

Classical enhancers couple cis-regulatory logic with transcriptional condensates and 3D genome architecture

Ville Tiusanen, Divyesh Patel, Jihan Xia, et al.

Selected by 22 March 2026

Siddharth Singh

Discussion

'Preprints by preLighters': Cell loss disrupts mechanical homeostasis to drive retinal pigment epithelium ageing-like phenotype in vitro

Teodora Piskova, Aleksandra N. Kozyrina, Giedrė Astrauskaitė, et al.

Selected by 03 March 2026

Reinier Prosee, Teodora Piskova

Cross Sectional and Longitudinal Imaging Reveals Spatiotemporal Divergence in Morphogenesis and Cell Lineage Specification between in-vivo and in-vitro Mouse Embryo during Pre- and Peri-implantation

Huanhuan Yang

Selected by 19 February 2026

Heather Pollington