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Quantification of microenvironmental metabolites in murine cancer models reveals determinants of tumor nutrient availability

Mark R Sullivan, Laura V Danai, Caroline A Lewis, et al.

Selected by 11 February 2019

Maria Rafaeva

Cancer Biology

Lineage tracing on transcriptional landscapes links state to fate during differentiation

Caleb Weinreb, Alejo E Rodriguez-Fraticelli, Fernando D Camargo, et al.

Selected by 05 February 2019

Yen-Chung Chen

Bioinformatics

A complex containing lysine-acetylated actin inhibits the formin inF2

Mu A, Tak Shun Fung, Arminja N. Kettenbach, et al.

Selected by 25 January 2019

Laura McCormick

Biochemistry

Variability of bacterial behavior in the mammalian gut captured using a growth-linked single-cell synthetic gene oscillator

David T Riglar, David L Richmond, Laurent Potvin-Trottier, et al.

Selected by 25 January 2019

Meng Zhu

Synthetic Biology

A Rap1 binding site and lipid-dependent helix in talin F1 domain cooperate in integrin activation

Alexandre Gingras, Frederic Lagarrigue, Monica Cuevas, et al.

Selected by 20 January 2019

Amanda Haage

A schizophrenia risk gene, NRGN, bidirectionally modulates synaptic plasticity via regulating the neuronal phosphoproteome

Hongik Hwang, Matthew J Szucs, Lei J Ding, et al.

Selected by 17 January 2019

Laura McCormick

Neuroscience

Atlas of Subcellular RNA Localization Revealed by APEX-seq

Furqan M Fazal, Shuo Han, Pornchai Kaewsapsak, et al.

AND

Proximity RNA labeling by APEX-Seq Reveals the Organization of Translation initiation Complexes and Repressive RNA Granules

Alejandro Padron, Shintaro Iwasaki, Nicholas ingolia

Selected by 14 January 2019

Christian Bates

Molecular Biology

Phase transition and amyloid formation by a viral protein as an additional molecular mechanism of virus-induced cell toxicity

Edoardo Salladini, Claire Debarnot, Vincent Delauzun, et al.

Selected by 11 January 2019

Tessa Sinnige

Biophysics

Stable knockout and complementation of receptor expression using in vitro cell line derived reticulocytes for dissection of host malaria invasion requirements

Timothy J Satchwell, Katherine E Wright, Katy L Haydn-Smith, et al.

Selected by 08 January 2019

Alyson Smith

Cell Biology

Maintenance of spatial gene expression by Polycomb-mediated repression after formation of a vertebrate body plan

Julien Rougot, Naomi D Chrispijn, Marco Aben, et al.

Selected by 07 January 2019

Yen-Chung Chen

Cell Biology

Activation of intracellular transport by relieving KIF1C autoinhibition

Nida Siddiqui, Alice Bachmann, Alexander J Zwetsloot, et al.

Selected by 07 January 2019

Ben Craske, Gaetan Dias Mirandela, Thibault Legal and Toni McHugh

Cell Biology

Embryo geometry drives formation of robust signaling gradients through receptor localization

Zhechun Zhang, Steven Zwick, Ethan Loew, et al.

Selected by 03 January 2019

Paul Gerald L. Sanchez and Stefano Vianello

Developmental Biology