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Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel Binding Modality and Mechanism of Action

Kevin Wilhelmsen, Aditi Deshpande, Sarah Tronnes, et al.

Selected by 13 February 2025

Roberto Amadio

Biochemistry

Mechanical stresses govern myoblast fusion and myotube growth

Yoann Le Toquin, Sushil Dubey, Aleksandra Ardaševa, et al.

Selected by 29 January 2025

Vibha SINGH, Prasanna Padmanaban

Cell Biology

Factor XI localization in human deep venous thrombus and function of activated factor XI on venous thrombus formation and hemostasis in rabbit

Nobuyuki Oguri, Toshihiro Gi, Eriko Nakamura, et al.

Selected by 03 January 2025

Adriani Felix et al.

Biochemistry

Restoring mechanophenotype reverts malignant properties of ECM-enriched vocal fold cancer

Jasmin Kaivola, Karolina Punovuori, Megan R. Chastney, et al.

Selected by 19 December 2024

Teodora Piskova

Cancer Biology

Leukocytes use endothelial membrane tunnels to extravasate the vasculature

Werner J. van der Meer, Abraham C.I. van Steen, Eike Mahlandt, et al.

Selected by 08 December 2024

Felipe Del Valle Batalla

Cell Biology

Actin-based deformations of the nucleus control multiciliated ependymal cell differentiation

Marianne Basso, Alexia Mahuzier, Syed Kaabir Ali, et al.

Selected by 30 October 2024

Ryan Harrison

Developmental Biology

Long range mutual activation establishes Rho and Rac polarity during cell migration

Henry De Belly, Andreu Fernandez Gallen, Evelyn Strickland, et al.

Selected by 22 October 2024

Vibha SINGH

Cell Biology

Golgi compaction facilitates microtubule nucleation to drive adult vertebrate peripheral neuron regeneration

Alice E Mortimer, Adam J Reid, Raman M Das

Selected by 15 October 2024

Vibha SINGH

Cell Biology

HIF1A contributes to the survival of aneuploid and mosaic pre-implantation embryos

Estefania Sanchez-Vasquez, Marianne E. Bronner, Magdalena Zernicka-Goetz

Selected by 11 October 2024

Anchel De Jaime Soguero

Developmental Biology

Axis reset is rate limiting for onset of whole-body regenerative abilities during planarian development

Clare L.T. Booth, Brian C. Stevens, Clover A. Stubbert, et al.

Selected by 10 October 2024

Isabella Cisneros

Developmental Biology

Feedback regulation by the RhoA-specific GEF ARHGEF17 regulates actomyosin network disassembly

Vasundhara Rao, Benjamin Grädel, Lucien Hinderling, et al.

Selected by 18 September 2024

Vibha SINGH

Cell Biology

Triglyceride metabolism controls inflammation and APOE4-associated disease states in microglia

Roxan A. Stephenson, Kory R. Johnson, Linling Cheng, et al.

Selected by 22 August 2024

Gustavo Stelzer, Marcus Oliveira

Biochemistry