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Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease

Richard J. Wheeler, Hyun O. Lee, Ina Poser, et al.

Selected by 30 August 2019

Madhuja Samaddar

Cell Biology

Isolation of an archaeon at the prokaryote-eukaryote interface

Hiroyuki Imachi, Masaru K. Nobu, Nozomi Nakahara, et al.

Selected by 15 August 2019

Dey Lab

Cell Biology

Cholesterol and matrisome pathways dysregulated in human APOE ε4 glia

Julia TCW, Shuang A. Liang, Lu Qian, et al.

Selected by 12 August 2019

Theresa Pohlkamp

Neuroscience

Apicomplexan F-actin is required for efficient nuclear entry during host cell invasion

Mario Del Rosario, Javier Periz, Georgios Pavlou, et al.

Selected by 04 June 2019

Juan Quintana

Microbiology

Spontaneous isomerization of long-lived proteins provides a molecular mechanism for the lysosomal failure observed in Alzheimer’s disease

Tyler R. Lambeth, Dylan L. Riggs, Lance E. Talbert, et al.

Selected by 15 May 2019

Joanna Cross

Biochemistry

SorCS1-mediated Sorting of Neurexin in Dendrites Maintains Presynaptic Function

Luis Filipe Ribeiro, Ben Verpoort, Julie Nys, et al.

Selected by 27 February 2019

Carmen Adriaens

Cell Biology

SLC19A1 is a cyclic dinucleotide transporter

Rutger Luteijn, Shivam Zaver, Benjamin G Gowen, et al.

AND

SLC19A1 is an importer of the immunotransmitter cGAMP

Anthony F. Cordova, Christopher Ritchie, Gaelen T. Hess, et al.

AND

2'3'-cGAMP is an immunotransmitter produced by cancer cells and regulated by ENPP1

Jacqueline A Carozza, Volker Boehnert, Kelsey E Shaw, et al.

Selected by 13 February 2019

Connor Rosen

Immunology

Activation of intracellular transport by relieving KIF1C autoinhibition

Nida Siddiqui, Alice Bachmann, Alexander J Zwetsloot, et al.

Selected by 07 January 2019

Ben Craske, Gaetan Dias Mirandela, Thibault Legal and Toni McHugh

Cell Biology

Transient intracellular acidification regulates the core transcriptional heat shock response

Catherine G Triandafillou, Christopher D Katanski, Aaron R Dinner, et al.

Selected by 25 September 2018

Srivats Venkataramanan

Cell Biology

ER-to-Golgi trafficking of procollagen in the absence of large carriers.

Janine McCaughey, Nicola Stevenson, Stephen Cross, et al.

Selected by 26 July 2018

Dey Lab

Cell Biology

The Histone H3-H4 Tetramer is a Copper Reductase Enzyme

Narsis Attar, Oscar A Campos, Maria Vogelauer, et al.

Selected by 18 July 2018

Lauren Neves

Molecular Biology

A new calcium-activated dynein adaptor protein, CRACR2a, regulates clathrin-independent endocytic traffic in T cells

Yuxiao Wang, Walter Huynh, Taylor Skokan, et al.

Selected by 04 July 2018

Nicola Stevenson

Cell Biology