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Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair

Marieke R. Wensveen, Aditya A. Dixit, Serafin U. Colmenares, et al.

Selected by 15 December 2023

Pierre Caron

Molecular Biology

Tardigrades dramatically upregulate DNA repair pathway genes in response to ionizing radiation

Courtney M. Clark-Hachtel, Jonathan D. Hibshman, Tristan De Buysscher, et al.

Selected by 18 October 2023

Isabella Cisneros

Genomics

Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis

Camille Gelot, Marton Tibor Kovacs, Simona Miron, et al.

Selected by 05 June 2023

Pierre Caron

Molecular Biology

BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote replication fork stability and continuous DNA synthesis

Daniel Salas-Lloret, Néstor García-Rodríguez, Lisanne Giebel, et al.

Selected by 09 March 2023

Pierre Caron

Cancer Biology

Pin1-promoted SUMOylation of RNF168 restrains its chromatin accumulation

Anoop Singh Chauhan, Alexander J. Garvin, Mohammed Jamshad, et al.

Selected by 20 June 2022

Pierre Caron

Biochemistry

cGAS recruitment to micronuclei is dictated by pre-existing nuclear chromatin status

Kate M. MacDonald, Shirony Nicholson-Puthenveedu, Maha M. Tageldein, et al.

Selected by 01 February 2022

Roberto Amadio

Cell Biology

Two redundant ubiquitin-dependent pathways of BRCA1 localization to DNA damage sites

Alana Sherker, Natasha Chaudhary, Salomé Adam, et al.

Selected by 10 August 2021

Giuseppina D'Alessandro

Cell Biology

Hyperactive end joining repair mediates resistance to DNA damaging therapy in p53-deficient cells

Rashmi J. Kumar, Hui Xiao Chao, Victoria R. Roberts, et al.

Selected by 24 June 2020

Matthew Burke

Cell Biology

A limited number of double-strand DNA breaks are sufficient to delay cell cycle progression.

Jeroen van den Berg, Anna G. Manjon, Karoline Kielbassa, et al.

Selected by 01 August 2018

Leighton Daigh

Cell Biology

Soil microbial habitats in an extreme desert Mars-analogue environment

Kimberley Warren-Rhodes, Kevin Lee, Stephen Archer, et al.

Selected by 26 July 2018

Daphne Ng

Microbiology