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Cell polarity linked to gravity sensing is generated by protein translocation from statoliths to the plasma membrane

Takeshi Nishimura, Shogo Mori, Hiromasa Shikata, et al.

AND

Amyloplast sedimentation repolarizes LAZYs to achieve gravity sensing in plants

Jiayue Chen, Renbo Yu, Na Li, et al.

Spatial and single-cell transcriptomics reveal neuron-astrocyte interplay in long-term memory

Wenfei Sun, Zhihui Liu, Xian Jiang, et al.

Discussion

Phosphoproteomics of cellular mechanosensing reveals NFATC4 as a regulator of myofibroblast activity

Laura F. Mattner, Zhen Zeng, Christoph H. Mayr, et al.

3D genome organization around nuclear speckles drives mRNA splicing efficiency

Prashant Bhat, Amy Chow, Benjamin Emert, et al.

Restructuring of an asymmetric neural circuit during associative learning

Leo T.H. Tang, Garrett A. Lee, Steven J. Cook, et al.

Discussion

An improved Erk biosensor reveals oscillatory Erk dynamics driven by mitotic erasure during early development

Scott G. Wilcockson, Luca Guglielmi, Pablo Araguas Rodriguez, et al.

Proteolysis-free cell migration through crowded environments via mechanical worrying

Meghan K. Driscoll, Erik S. Welf, Andrew Weems, et al.

ARHGEF18 participates in Endothelial Cell Mechano-sensitivity in Response to Flow

Surya Prakash Rao Batta, Marc Rio, Corentin Lebot, et al.

Discussion

An Arp2/3-cPLA2-NFκB axis acts as a Cell Shape Sensor to drive Homeostatic Migration of Dendritic Cells

Zahraa Alraies, Claudia A. Rivera, Maria-Graciela Delgado, et al.

An intestinal sphingolipid promotes neuronal health across generations

Wenyue Wang, Tessa Sherry, Xinran Cheng, et al.

MPS1 localizes to microtubule-attached kinetochores and actively promotes microtubule release

Daniel Hayward, Emile Roberts, Ulrike Gruneberg

Induction of cortical Par complex polarity by designed proteins causes cytoskeletal symmetry breaking in unpolarized mammalian cells

Joseph L. Watson, Ariel J. Ben-Sasson, Alice Bittleston, et al.