Search results

Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel Binding Modality and Mechanism of Action

Kevin Wilhelmsen, Aditi Deshpande, Sarah Tronnes, et al.

Selected by 13 February 2025

Roberto Amadio

Discussion

Factor XI localization in human deep venous thrombus and function of activated factor XI on venous thrombus formation and hemostasis in rabbit

Nobuyuki Oguri, Toshihiro Gi, Eriko Nakamura, et al.

Selected by 03 January 2025

Adriani Felix et al.

Discussion

A fine kinetic balance of interactions directs transcription factor hubs to genes

Apratim Mukherjee, Samantha Fallacaro, Puttachai Ratchasanmuang, et al.

Selected by 23 July 2024

Deevitha Balasubramanian

Mixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets

John M. Bennett, Sunil K. Narwal, Stephanie Kabeche, et al.

Selected by 02 February 2024

Zhang-He Goh

Discovery and Validation of Context-Dependent Synthetic Mammalian Promoters

Adam M. Zahm, William S. Owens, Samuel R. Himes, et al.

Selected by 21 June 2023

Jessica L. Teo

Biologically informed NeuralODEs for genome-wide regulatory dynamics

Intekhab Hossain, Viola Fanfani, John Quackenbush, et al.

Selected by 31 May 2023

Benjamin Dominik Maier

Susceptible bacteria survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance

Marinelle Rodrigues, Parastoo Sabaeifard, Muhammed Sadik Yildiz, et al.

Selected by 16 May 2023

UofA IMB565

DNA-enhanced CuAAC ligand enables live-cell detection of intracellular biomolecules

Keqing Nian, Yifang Liu, Laura Brigandi, et al.

Selected by 23 December 2022

Zhang-He Goh

Discussion

Multifunctional fluorophores for live-cell imaging and affinity capture of proteins

Pratik Kumar, Jason D. Vevea, Edwin R. Chapman, et al.

Selected by 19 August 2022

Zhang-He Goh

Discussion

Selective inhibitors of JAK1 targeting a subtype-restricted allosteric cysteine

Madeline E. Kavanagh, Benjamin D. Horning, Roli Khattri, et al.

Selected by 13 March 2022

Zhang-He Goh

Discussion

CDK9 and PP2A regulate the link between RNA polymerase II transcription termination and RNA maturation

Michael Tellier, Justyna Zaborowska, Jonathan Neve, et al.

Selected by 02 November 2021

Isabella Maudlin

Hedgehog signaling can enhance glycolytic ATP production in the Drosophila wing disc

Ioannis Nellas, K. Venkatesan Iyer, Juan M. Iglesias-Artola, et al.

Selected by 08 October 2021

Julia Grzymkowski