A genome-wide knock-out screen for actors of epigenetic silencing reveals new regulators of germline genes and 2-cell like cell state
Selected by
15 June 2021
María Mariner-Faulí

Enhancer-associated H3K4 methylation safeguards in vitro germline competence
Selected by
13 May 2021
Sree Rama Chaitanya

Redundant mechanisms driven independently by RUNX1 and GATA2 for haematopoietic development
Selected by
16 April 2021
Tim Petzold

Mitotic R-loops direct Aurora B kinase to maintain centromeric cohesion
Selected by
10 February 2021
Jennifer Ann Black

SF3B1-targeted Splicing Inhibition Triggers Global Alterations in Transcriptional Dynamics and R-Loop Metabolism
Selected by
06 November 2020
Sree Rama Chaitanya

A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic
AND
Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses
Selected by
31 July 2020
Yen-Chung Chen

BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity
Selected by
14 July 2020
Louise Fraser

Endogenous retroviruses are a source of enhancers with oncogenic potential in acute myeloid leukaemia
Selected by
21 April 2020
Jesus Victorino

Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits
Selected by
18 June 2019
Pavithran Ravindran

Molecularly distinct models of zebrafish Myc-induced B cell leukemia
Selected by
03 December 2018
Hannah Brunsdon

Systematic identification of human SNPs affecting regulatory element activity
Selected by
29 November 2018
Jesus Victorino
Genetically regulated human NODAL splice variants are differentially post-transcriptionally processed and functionally distinct
Selected by
03 April 2018
Pierre Osteil
