A genome-wide knock-out screen for actors of epigenetic silencing reveals new regulators of germline genes and 2-cell like cell state
Selected by
María Mariner-Faulí
Enhancer-associated H3K4 methylation safeguards in vitro germline competence
Selected by
Sree Rama Chaitanya
Redundant mechanisms driven independently by RUNX1 and GATA2 for haematopoietic development
Selected by
Tim Petzold
Mitotic R-loops direct Aurora B kinase to maintain centromeric cohesion
Selected by
Jennifer Ann Black
SF3B1-targeted Splicing Inhibition Triggers Global Alterations in Transcriptional Dynamics and R-Loop Metabolism
Selected by
Sree Rama Chaitanya
A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic
AND
Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses
Selected by
Yen-Chung Chen
BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity
Selected by
Louise Fraser
Endogenous retroviruses are a source of enhancers with oncogenic potential in acute myeloid leukaemia
Selected by
Jesus Victorino
Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits
Selected by
Pavithran Ravindran
Molecularly distinct models of zebrafish Myc-induced B cell leukemia
Selected by
Hannah Brunsdon
Systematic identification of human SNPs affecting regulatory element activity
Selected by
Jesus Victorino
Genetically regulated human NODAL splice variants are differentially post-transcriptionally processed and functionally distinct
Selected by
Pierre Osteil