Search results

Programmable pathway profiles reveal signaling principles of TGF-β superfamily receptors

Bo Gu, James M Linton, Brice Graham Hendrickson, et al.

Selected by 07 September 2026

Benjamin Swedlund, Charli Lu

Discussion

BAF complexes maintain accessibility at stimulus-responsive chromatin and are required for transcriptional stimulus responses

Alexander O. D. Gulka, Kihoon A. Kang, Ziben Zhou, et al.

Selected by 08 August 2026

Dina Kabbara

Aging increases ovarian cancer growth, metastasis, and immunosuppression that can be alleviated by inhibiting hedgehog signaling

Asha Kumari, Mohamed Halaby Elbahoty, Resha Rajkarnikar, et al.

Selected by 03 August 2026

Zoha Sadaqat

A pre-rRNA positive feedback loop drives malignant ribosome biogenesis

Emilie L. Alard, Martin Dodel, Shannon N. Russell, et al.

Selected by 02 August 2026

Vaishali Grewal

Comprehensive Lineage Tracing Maps the Landscape of Cell Fate Decisions in Mouse Embryogenesis

William N. Colgan, Luke W. Koblan, JoAnne Villagrana, et al.

Selected by 01 July 2026

Béryl Laplace-Builhé, Lucie Hermet

Discussion

Targeting CXADR-mediated AKT signaling suppresses tumorigenesis and enhances chemotherapy efficacy in Ewing sarcoma

Alina Ritter, Malenka Zimmermann, Florian H. Geyer, et al.

Selected by 09 June 2026

TheLangeLab et al.

Discussion

Dual inhibition of GTP-bound (ON) and GDP-bound (OFF) KRAS^G12C suppresses PI3Kα and leads to potent tumor inhibition

Katherine Parker, Samar Ghorbanpoor, Wafa Malik, et al.

Selected by 03 June 2026

Luis Luna Ramírez

Discussion

Deep Invaginations of Nuclear Envelope Coordinate Spatial Organization of Chromatin in Epithelium

Elina Mäntylä, Sanna Korpela, Anna Rekonen, et al.

Selected by 02 June 2026

Abby Hein

Discussion

Generalization and extinction of learned fear alter primary sensory input to the brain

Michelle C. Rosenthal, Alper K. Bakir, John P. McGann

Selected by 21 May 2026

Kathleen Ngo et al.

Discussion

Cardiac-immune microniches programme macrophage states in the regenerating heart

Ehsan Razaghi, Selin Tüzüner, Trishalee Gungoosingh, et al.

Selected by 19 May 2026

Theodora Stougiannou

Small Molecule Agonists of TREM2 Reprogram Microglia and Protect Synapses in Human Alzheimer’s Models

Hossam Nada, Shaoren Yuan, Farida El Gaamouch, et al.

Selected by 17 March 2026

Dina Kabbara

The lipidomic architecture of the mouse brain

Luca Fusar Bassini, Halima Hannah Schede, Laura Capolupo, et al.

Selected by 09 February 2026

IRR UoE Journal Club et al.

Discussion