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Inference of drug off-target effects on cellular signaling using Interactome-Based Deep Learning

Nikolaos Meimetis, Douglas A. Lauffenburger, Avlant Nilsson

Olfactory chemosensation extends lifespan through TGF-β signaling and UPR activation

Evandro A. De-Souza, Maximillian A. Thompson, Rebecca C. Taylor

Comparative analysis of cattle breeds as satellite cell donors for cultured beef

Lea Melzener, Shijie Ding, Rui Hueber, et al.

Isolation disrupts social interactions and destabilizes brain development in bumblebees

Z Yan Wang, Grace C. McKenzie-Smith, Weijie Liu, et al.

piRNAs regulate a Hedgehog germline-to-soma pro-aging signal

Cheng Shi, Coleen T. Murphy

Sexual conflict promotes species coexistence through negative frequency dependence

Miguel Gomez-Llano, Sofie Nilén, Iain Moodie, et al.

Th17 cell master transcription factor RORC2 regulates HIV-1 gene expression and viral outgrowth

Tomas Raul Wiche Salinas, Yuwei Zhang, Daniele Sarnello, et al.

Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth

Suprit Gupta, Julian Yano, Htet Htwe Htwe, et al.

A mating-induced reproductive gene promotes Anopheles tolerance to Plasmodium falciparum infection

Perrine Marcenac, W. Robert Shaw, Evdoxia G. Kakani, et al.

Interspecies differences in proteome turnover kinetics are correlated with lifespans and energetic demands

Kyle Swovick, Denis Firsanov, Kevin A. Welle, et al.

ER-Mitochondria Contacts Promote Mitochondrial-Derived Compartment Biogenesis

Alyssa M. English, Benoît Kornmann, Janet M. Shaw, et al.

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Mitochondrial-Derived Compartments Facilitate Cellular Adaptation to Amino Acid Stress

Max-Hinderk Schuler, Alyssa M. English, Thane J. Campbell, et al.

KDM6B-dependent chromatin remodelling underpins effective virus-specific CD8⁺ T cell differentiation

Jasmine Li, Kristine Hardy, Moshe Olshansky, et al.