Large-scale curvature sensing by epithelial monolayers depends on active cell mechanics and nuclear mechanoadaptation
Selected by
Grace Lim, Ilaria Di Meglio
A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute lung Injury during the COVID-19 pandemic
AND
Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses
Selected by
Yen-Chung Chen
Electron Transfer from Cytochrome P450 Reductase to Cytochrome P450: Towards a Structural and Dynamic Understanding
Selected by
Zhang-He Goh
Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen
AND
Tamoxifen reduces inflammatory infiltration of neutrophils in the airways
Selected by
Zhang-He Goh, Josie Gibson
Human alveolar Type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells during alveolar repair
Selected by
Julio Sainz de Aja
A lung-on-chip model reveals an essential role for alveolar epithelial cells in controlling bacterial growth during early tuberculosis
Selected by
Snehal Kadam
Epithelial Tissues as Active Solids: From Nonlinear Contraction Pulses to Rupture Resistance
Selected by
Mariana De Niz
Preserved efficacy and reduced toxicity with intermittent linezolid dosing in combination with bedaquiline and pretomanid in a murine TB model
Selected by
Zhang-He Goh
Trophic cooperation promotes bacterial survival of Staphylococcus aureus and Pseudomonas aeruginosa
Selected by
Josie Gibson
Neural plate targeting by in utero nanoinjection (NEPTUNE) reveals a role for Sptbn2 in neurulation and abdominal wall closure
Selected by
Martin Estermann
Broad-spectrum antivirals of protoporphyrins inhibit the entry of highly pathogenic emerging viruses
Selected by
Zhang-He Goh
Organoid Easytag: an efficient workflow for gene targeting in human organoids
Selected by
Kirsty Ferguson