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Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification

Sherine E. Thomas, Andrew J. Whitehouse, Karen Brown, et al.

SLC19A1 is a cyclic dinucleotide transporter

Rutger Luteijn, Shivam Zaver, Benjamin G Gowen, et al.

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SLC19A1 is an importer of the immunotransmitter cGAMP

Anthony F. Cordova, Christopher Ritchie, Gaelen T. Hess, et al.

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2'3'-cGAMP is an immunotransmitter produced by cancer cells and regulated by ENPP1

Jacqueline A Carozza, Volker Boehnert, Kelsey E Shaw, et al.

A conserved MFS orchestrates a subset of O-glycosylation to facilitate macrophage dissemination and tissue invasion

Katarina Valoskova, Julia Biebl, Marko Roblek, et al.

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Activation of intracellular transport by relieving KIF1C autoinhibition

Nida Siddiqui, Alice Bachmann, Alexander J Zwetsloot, et al.

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Developmental heterogeneity of microglia and brain myeloid cells revealed by deep single-cell RNA sequencing

Qingyun Li, Zuolin Cheng, Lu Zhou, et al.

PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection

Catherine M Buckley, Victoria L Heath, Aurelie Gueho, et al.

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The cytoskeleton as a smart composite material: A unified pathway linking microtubules, myosin-II filaments and integrin adhesions

Nisha Mohd Rafiq, Yukako Nishimura, Sergey V. Plotnikov, et al.

Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages is necessary for functional spinal cord regeneration in zebrafish

Themistoklis M. Tsarouchas, Daniel Wehner, Leonardo Cavone, et al.

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Human macrophages survive and adopt activated genotypes in living zebrafish

Colin D. Paul, Alexus Devine, Kevin Bishop, et al.

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Single-cell Map of Diverse Immune Phenotypes Driven by the Tumor Microenvironment

Elham Azizi, Ambrose J. Carr, George Plitas, et al.

Size-dependent segregation controls macrophage phagocytosis of antibody-opsonized targets

Matthew H Bakalar, Aaron M Joffe, Eva Schmid, et al.