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SQ3370, the first clinical click chemistry-activated cancer therapeutic, shows safety in humans and translatability across species

Sangeetha Srinivasan, Nathan A. Yee, Michael Zakharian, et al.



Selected by Zhang-He Goh

ProteasomeID: quantitative mapping of proteasome interactomes and substrates for in vitro and in vivo studies

Aleksandar Bartolome, Julia C. Heiby, Therese Dau, et al.



Selected by Aniruddha Das

massively parallel protein-protein interaction measurement by sequencing (MP3-seq) enables rapid screening of protein heterodimers

Alexander Baryshev, Alyssa La Fleur, Benjamin Groves, et al.



Selected by Benjamin Dominik Maier

BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote replication fork stability and continuous DNA synthesis

Daniel Salas-Lloret, Néstor García-Rodríguez, Lisanne Giebel, et al.



Selected by Pierre Caron

Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment

Julia Kolb, Nora John, Kyoohyun Kim, et al.



Selected by Laura Celotto

VAP spatially stabilizes dendritic mitochondria to locally fuel synaptic plasticity

Ojasee Bapat, Tejas Purimetla, Sarah Kruessel, et al.



Selected by Kritika Mehta

Differential mosquito attraction to humans is associated with skin-derived carboxylic acid levels

Maria Elena De Obaldia, Takeshi Morita, Laura C. Dedmon, et al.



Selected by Kristina Kuhbandner

A supergene in seaweed flies modulates male traits and female perception

Swantje Enge, Claire Mérot, Raimondas Mozūraitis, et al.



Selected by Riddhi Deshmukh

Discovery and visualization of uncharacterized drug-protein adducts using mass spectrometry

Michael Riffle, Michael R. Hoopmann, Daniel Jaschob, et al.



Selected by Zhang-He Goh

Scaling of cellular proteome with ploidy

Galal Yaha, Paul Menges, Devi Anggraini Ngandiri, et al.



Selected by Jennifer Ann Black

Integration of Protein Interactome Networks with Congenital Heart Disease Variants Reveals Candidate Disease Genes

Barbara Gonzalez-Teran, Maureen Pittman, Franco Felix, et al.



Selected by Alexander Ward

A “spindle and thread”-mechanism unblocks translation of N-terminally disordered proteins

Margit Kaldmäe, Thibault Vosselman, Xueying Zhong, et al.



Selected by Utrecht Protein Folding and Assembly
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