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Evolutionarily diverse LIM domain-containing proteins bind stressed actin filaments through a conserved mechanism

Jonathan D. Winkelman, Caitlin A. Anderson, Cristian Suarez, et al.

AND

Mechanosensing through direct binding of tensed F-actin by LIM domains

Xiaoyu Sun, Donovan Y. Z. Phua, Lucas Axiotakis Jr., et al.

Sensory input drives rapid homeostatic scaling of the axon initial segment in mouse barrel cortex

Nora Jamann, Dominik Dannehl, Robin Wagener, et al.

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

David E. Gordon, Gwendolyn M. Jang, Mehdi Bouhaddou, et al.

Unstructured mRNAs form multivalent RNA-RNA interactions to generate TIS granule networks

Weirui Ma, Gang Zhen, Wei Xie, et al.

ER-Mitochondria Contacts Promote Mitochondrial-Derived Compartment Biogenesis

Alyssa M. English, Benoît Kornmann, Janet M. Shaw, et al.

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Mitochondrial-Derived Compartments Facilitate Cellular Adaptation to Amino Acid Stress

Max-Hinderk Schuler, Alyssa M. English, Thane J. Campbell, et al.

Discussion

Opposing influence of top-down and bottom-up input on different types of excitatory layer 2/3 neurons in mouse visual cortex

Rebecca Jordan, Georg Keller

ActuAtor, a molecular tool for generating force in living cells: Controlled deformation of intracellular structures

Hideki Nakamura, Elmer Rho, Daqi Deng, et al.

Discussion

The single flagellum of Leishmania has a fixed polarisation of its asymmetric beat

Ziyin Wang, Tom Beneke, Eva Gluenz, et al.

The molecular structure of primary cilia revealed by cryo-electron tomography

Petra Kiesel, Gonzalo Alvarez Viar, Nikolai Tsoy, et al.

CryoEM structure of the Vibrio cholerae Type IV competence pilus secretin PilQ

Sara J. Weaver, Matthew H. Sazinsky, Triana N. Dalia, et al.

Discussion

Constricted migration contributes to persistent 3D genome structure changes associated with an invasive phenotype in melanoma cells

Rosela Golloshi, Rebeca San Martin, Priyojit Das, et al.

Mitochondrial fission factor (MFF) is a critical regulator of peroxisome maturation

Josiah B. Passmore, Ruth E. Carmichael, Tina A. Schrader, et al.