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Embryo geometry drives formation of robust signaling gradients through receptor localization

Zhechun Zhang, Steven Zwick, Ethan Loew, et al.

Selected by 03 January 2019

Paul Gerald L. Sanchez and Stefano Vianello

Developmental Biology

Biofilm/Persister/Stationary Phase Bacteria Cause More Severe Disease Than Log Phase Bacteria II Infection with Persister Forms of Staphylococcus aureus Causes a Chronic Persistent Skin Infection with More Severe Lesion that Takes Longer to Heal and is not Eradicated by the Current Recommended Treatment in Mice

Rebecca Yee, Yuting Yuan, Cory Brayton, et al.

Selected by 20 December 2018

Snehal Kadam

Microbiology

Psychiatric risk gene NT5C2 regulates protein translation in human neural progenitor cells

Rodrigo R.R. Duarte, Nathaniel D. Bachtel, Marie-Caroline Cotel, et al.

Selected by 07 December 2018

Joanna Cross

Neuroscience

A Scube2-Shh feedback loop links morphogen release to morphogen signaling to enable scale invariant patterning of the ventral neural tube

Zach Collins, Kana Ishimatsu, Tony Tsai, et al.

Selected by 03 December 2018

Teresa Rayon

Developmental Biology

Epiblast formation by Tead-Yap-dependent expression of pluripotency factors and competitive elimination of unspecified cells

Masakazu Hashimoto, Hiroshi Sasaki

Selected by 29 November 2018

Sarah Bowling, Teresa Rayon

Developmental Biology

Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord

Julien Delile, Teresa Rayon, Manuela Melchionda, et al.

Selected by 28 November 2018

Reena Lasrado

Developmental Biology

Molecular organization of integrin-based adhesion complexes in mouse Embryonic Stem Cells

Shumin Xia, Evelyn K.F. Yim, Pakorn Kanchanawong

AND

Superresolution architecture of pluripotency guarding adhesions

Aki Stubb, Camilo Guzmán, Elisa Närvä, et al.

Selected by 02 November 2018

Nicola Stevenson, Amanda Haage

Cell Biology

Revealing the nanoscale morphology of the primary cilium using super-resolution fluorescence microscopy

Joshua Yoon, Colin J. Comerci, Lucien E. Weiss, et al.

Selected by 19 October 2018

Dey Lab

Cell Biology

Three-dimensional tissue stiffness mapping in the mouse embryo supports durotaxis during early limb bud morphogenesis

Min Zhu, Hirotaka Tao, Mohammad Samani, et al.

Selected by 15 October 2018

Natalie Dye

Biophysics

PUMILIO hyperactivity drives premature aging of Norad-deficient mice

Florian Kopp, Mehmet Yalvac, Beibei Chen, et al.

Selected by 09 October 2018

Carmen Adriaens

Genetics

Arterio-Venous Remodeling in the Zebrafish Trunk Is Controlled by Genetic Programming and Flow-Mediated Fine-Tuning

Ilse Geudens, Baptiste Coxam, Silvanus Alt, et al.

Selected by 24 September 2018

Andreas van Impel

Developmental Biology

LCM-seq reveals unique transcriptional adaption mechanisms of resistant neurons in spinal muscular atrophy

Susanne Nichterwitz, Helena Storvall, Jik Nijssen, et al.

AND

Axon-seq decodes the motor axon transcriptome and its modulation in response to ALS

Jik Nijssen, Julio Cesar Aguila Benitez, Rein Hoogstraaten, et al.

Selected by 12 September 2018

Yen-Chung Chen

Systems Biology