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Ancient origins of complex neuronal genes

Matthew J. McCoy, Andrew Z. Fire

Selected by 23 October 2023

Preethi Krishnaraj, Chee Kiang Ewe

Evolutionary Biology

Short N-terminal disordered regions and the proline-rich domain are major regulators of phase transitions for full-length UBQLN1, UBQLN2 and UBQLN4

Thuy P. Dao, Anitha Rajendran, Sarasi K. K. Galagedera, et al.

Selected by 22 October 2023

Aniruddha Das

Biochemistry

NAD+ metabolism is a key modulator of bacterial respiratory epithelial infections

Björn Klabunde, André Wesener, Wilhelm Bertrams, et al.

Selected by 17 October 2023

Matheus Atella de Oliveira, Marcus Oliveira

Immunology

NAD(H) homeostasis is essential for host protection mediated by glycolytic myeloid cells in tuberculosis

Hayden T. Pacl, Krishna C. Chinta, Vineel P. Reddy, et al.

Selected by 16 October 2023

Matheus Atella de Oliveira, Marcus Oliveira

Biochemistry

Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions

Mrityunjoy Kar, Laura T. Vogel, Gaurav Chauhan, et al.

Selected by 03 October 2023

Erich Sohn

Biochemistry

CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

Madison B. Adolph, Atharv S. Garje, Swati Balakrishnan, et al.

Selected by 06 September 2023

Jessica Chevallier, Pierre Caron

Cell Biology

Proteasome condensate formation is driven by multivalent interactions with shuttle factors and K48-linked ubiquitin chains

Kenrick A. Waite, Gabrielle Vontz, Stella Y. Lee, et al.

Selected by 05 September 2023

Aniruddha Das

Biochemistry

PYCR1 Levels Track with Premature and Chronological Skin Aging

Kortessa Sotiropoulou, Saniye Yumlu, Tomoko Hirano, et al.

Selected by 17 August 2023

Preethi Krishnaraj

Genetics

Conserved cardiolipin-mitochondrial ADP/ATP carrier interactions assume distinct structural and functional roles that are clinically relevant

Nanami Senoo, Dinesh K. Chinthapalli, Matthew G. Baile, et al.

Selected by 14 July 2023

Barbora Knotkova

Biochemistry

A transposase-derived gene required for human brain development

Luz Jubierre Zapater, Elias Rodriguez-Fos, Merce Planas-Felix, et al.

Selected by 06 July 2023

Amanda Ivanoff

Developmental Biology

DNA methylation rates scale with maximum lifespan across mammals

Samuel. J. C. Crofts, Eric Latorre-Crespo, Tamir Chandra

Selected by 13 June 2023

Jennifer Ann Black

Genetics

Glioblastoma extracellular vesicles influence glial cell hyaluronic acid deposition to promote invasiveness

Dominik Koessinger, David Novo, Anna Koessinger, et al.

Selected by 13 June 2023

Jade Chan

Cancer Biology