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Short n-terminal disordered regions and the proline-rich domain are major regulators of phase transitions for full-length UBQLN1, UBQLN2 and UBQLN4

Thuy P. Dao, Anitha Rajendran, Sarasi K. K. Galagedera, et al.

Selected by 22 October 2023

Aniruddha Das

Biochemistry

Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions

Mrityunjoy Kar, Laura T. Vogel, Gaurav Chauhan, et al.

Selected by 03 October 2023

Erich Sohn

Biochemistry

A deep mutational scanning platform to characterize the fitness landscape of anti-CRISPR proteins

Tobias Stadelmann, Daniel Heid, Michael Jendrusch, et al.

Selected by 03 September 2021

Soni Mohapatra

Bioengineering

A “spindle and thread”-mechanism unblocks translation of n-terminally disordered proteins

Margit Kaldmäe, Thibault Vosselman, Xueying Zhong, et al.

Selected by 16 April 2021

Utrecht Protein Folding and Assembly

Biochemistry

Structure of an infectious mammalian prion

Allison Kraus, Forrest Hoyt, Cindi L. Schwartz, et al.

Selected by 04 March 2021

Jennifer Ann Black

Biochemistry

SUV39 SET domains mediate crosstalk of heterochromatic histone marks

Alessandro Stirpe, Nora Guidotti, Sarah Northall, et al.

Selected by 03 July 2020

Yasmin Lau

Intrinsically disordered domain of kinesin-3 Kif14 enables unique functional diversity

Ilia Zhernov, Stefan Diez, Marcus Braun, et al.

Selected by 14 April 2020

Ben Craske, Gaetan Dias Mirandela, Thibault Legal and Toni McHugh

Biophysics

Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification

Sherine E. Thomas, Andrew J. Whitehouse, Karen Brown, et al.

Selected by 05 March 2019

Yasmin Lau

Phase transition and amyloid formation by a viral protein as an additional molecular mechanism of virus-induced cell toxicity

Edoardo Salladini, Claire Debarnot, Vincent Delauzun, et al.

Selected by 11 January 2019

Tessa Sinnige

Biophysics