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Combinatorial and Inducible CRISPRa/i Enables Canalized hiPSC Forward Programming and Iterative Refinement via Single-Cell Genomics

Federica Sozza, Alberto Romano, Nicole D’Elia, et al.

Selected by 01 July 2026

Cell-ID

Synthetic Biology

The Endocannabinoid System’s Contribution to Placebo Analgesia

Rossi Tomin, Kevin Murray, Georgia E. Hadjis, et al.

Selected by 04 June 2026

Thomas Nicodemo Arrieta et al.

Neuroscience

UFMylation of Pyruvate Dehydrogenase Regulates Mitochondrial Metabolism

Phong T. Nguyen, Zheng Wu, Dohun Kim, et al.

Selected by 20 April 2026

Hannah Pletcher

Biochemistry

4,5-dihydroxyhexanoic acid is a robust circulating and urine marker of mitochondrial disease and its severity

Owen S. Skinner, Maria Miranda, Fangcong Dong, et al.

Selected by 01 April 2026

Hannah Pletcher

Biochemistry

Small Molecule Agonists of TREM2 Reprogram Microglia and Protect Synapses in Human Alzheimer’s Models

Hossam nada, Shaoren Yuan, Farida El Gaamouch, et al.

Selected by 17 March 2026

Dina Kabbara

Pharmacology and Toxicology

Aspartate transaminases are required for blood development

Narges Pourmandi, Greggory Myers, Arjun Jha, et al.

Selected by 26 November 2025

Hannah Pletcher

Biochemistry

VANGL2 shapes the mouse heart tube from adjacent epithelia and without planar polarity

Paul Palmquist-Gomes, Gaëlle Letort, Ayushi U. Hegde, et al.

Selected by 19 November 2025

Anubhav Prakash

Developmental Biology

Beyond venomous fangs: Uloboridae spiders have lost their venom but not their toxicity

Xiaojing Peng, Ludwig Dersch, Josephine Dresler, et al.

Selected by 13 November 2025

Daniel Fernando Reyes Enríquez, Marcus Oliveira

Evolutionary Biology

Inhibition of NF-κB Signaling by the Reactive Glycolytic Metabolite Methylglyoxal

Caroline Stanton, Woojin Choi, R. Luke Wiseman, et al.

Selected by 10 November 2025

Yan Aveiro dos Reis, Marcus Oliveira

Biochemistry

The cold tolerance of an adult winter-active stonefly: How Allocapnia pygmaea (Plecoptera: Capniidae) avoids freezing in Nova Scotian winters

Jona Lopez Pedersen, Luke S. Burton, Tamara M. Rodela, et al.

Selected by 06 October 2025

Stefan Friedrich Wirth

Ecology

Single-Cell Network Analysis Identifies CLEC4E as a Key Mediator of Proinflammatory mDC Responses in Influenza Infection

Subin Cho, Gabriel Laghlali, Arturo Marin, et al.

Selected by 29 September 2025

Charis Qi

Systems Biology

TET knockout cells transit between pluripotent states and exhibit precocious germline entry

Raphaël Pantier, Elisa Barbieri, Sara Gonzalez Brito, et al.

Selected by 05 August 2025

Justin Gutkowski

Developmental Biology