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TDP-43 directly inhibits RNA accumulation in neurites through modulation of RNA stability

Charlie Moffatt, Ankita Arora, Katherine F. Vaeth, et al.

Selected by 10 April 2025

Felipe Del Valle Batalla

Cell Biology

Levetiracetam prevents Aβ42 production through SV2a-dependent modulation of App processing in Alzheimer’s disease models

Nalini R. Rao, Olivia DeGulis, Toshihiro Nomura, et al.

Selected by 11 January 2025

Jawdat Sandakly

Neuroscience

Polystyrene nanoplastics promote neurodegeneration by catalyzing TDP43 hyperphosphorylation

Winanto, Li-Yi Tan, Wai Hon Chooi, et al.

Selected by 08 January 2025

Manuel Lessi

Neuroscience

Triglyceride metabolism controls inflammation and APOE4-associated disease states in microglia

Roxan A. Stephenson, Kory R. Johnson, Linling Cheng, et al.

Selected by 22 August 2024

Gustavo Stelzer, Marcus Oliveira

Biochemistry

Impaired 26S proteasome causes learning and memory deficiency and induces neuroinflammation mediated by NF-κB in mice

Christa C. Huber, Eduardo Callegari, Maria Paez, et al.

Selected by 22 August 2024

Gustavo Stelzer, Marcus Oliveira

Biochemistry

Behavioral screening of conserved RNA-binding proteins reveals CEY-1/YBX RNA-binding protein dysfunction leads to impairments in memory and cognition

Ashley N Hayden, Katie L Brandel, Paul R Merlau, et al.

Selected by 15 February 2024

Chee Kiang Ewe

Animal Behavior and Cognition

Single-cell epigenomic reconstruction of developmental trajectories in human neural organoid systems from pluripotency

Fides Zenk, Jonas Simon Fleck, Sophie Martina Johanna Jansen, et al.

Selected by 04 January 2024

Manuel Lessi

Neuroscience

Therapeutic strategy for spinal muscular atrophy by combining gene supplementation and genome editing

Fumiyuki Hatanaka, Keiichiro Suzuki, Kensaku Shojima, et al.

Selected by 03 May 2023

Preethi Krishnaraj

Neuroscience

VAP spatially stabilizes dendritic mitochondria to locally fuel synaptic plasticity

Ojasee Bapat, Tejas Purimetla, Sarah Kruessel, et al.

Selected by 10 February 2023

Kritika Mehta

Biochemistry

Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality

Sonia Sabate-Soler, Sarah Louise Nickels, Cláudia Saraiva, et al.

Selected by 08 March 2022

Emma Wilson

Neuroscience

Neuronal activity drives pathway-specific depolarization of astrocyte distal processes

Moritz Armbruster, Saptarnab Naskar, Jacqueline Garcia, et al.

Selected by 20 July 2021

Kristina Kuhbandner

Neuroscience

Astrocyte plasticity ensures continued endfoot coverage of cerebral blood vessels and integrity of the blood brain barrier, with plasticity declining with normal aging

William A. Mills III, Shan Jiang, Joelle Martin, et al.

Selected by 20 July 2021

Ranabir Chakraborty

Neuroscience