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Neutrophil KLF2 regulates inflammasome-dependent neonatal mortality from endotoxemia

Devashis Mukherjee, Sriram Satyavolu, Asha Thomas, et al.

Selected by 28 May 2025

Sydney Call et al.

Immunology

Discovery of a Potent and Selective Inhibitor of Human nlrp3 with a Novel Binding Modality and Mechanism of Action

Kevin Wilhelmsen, Aditi Deshpande, Sarah Tronnes, et al.

Selected by 13 February 2025

Roberto Amadio

Biochemistry

BTK operates a phospho-tyrosine switch to regulate nlrp3 inflammasome activity

Zsófia A. Bittner, Xiao Liu, Sangeetha Shankar, et al.

Selected by 14 July 2020

Louise Fraser

Immunology

Conflicts with diarrheal pathogens trigger rapid evolution of an intestinal signaling axis

Clayton M. Carey, Sarah E. Apple, Zoё A. Hilbert, et al.

Selected by 17 April 2020

Connor Rosen

Evolutionary Biology