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Systematic analysis of protein targets associated with adverse events of drugs from clinical trials and post-marketing reports

Ines A. Smit, Avid M. Afzal, Chad H. G. Allen, et al.

AND

Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia

Hongbin Wan, Gianluca Selvaggio, Robert A. Pearlstein

Selected by 13 July 2020

Zhang-He Goh

Pharmacology and Toxicology

Miniaturized Devices for Bioluminescence Imaging in Freely Behaving Animals

Dmitrijs Celinskis, Nina Friedman, Mikhail Koksharov, et al.

Selected by 11 July 2020

Mariana De Niz

Bioengineering

Breaking the next Cryo-EM resolution barrier – Atomic resolution determination of proteins!

Ka Man Yip, Niels Fischer, Elham Paknia, et al.

Selected by 09 July 2020

Mariana De Niz

Biochemistry

Physical constraints on early blastomere packings

James Giammona, Otger Campàs

Selected by 09 July 2020

Sundar Naganathan

Biophysics

LIVE-PAINT: Super-Resolution Microscopy Inside Live Cells Using Reversible Peptide-Protein Interactions

Curran Oi, Zoe Gidden, Louise Holyoake, et al.

Selected by 11 June 2020

Xenia Meshik

Bioengineering

Subthreshold Voltage Analysis Demonstrates Neuronal Cell-Surface Sialic Acids Modulate Excitability and Network Integration

Rishikesh U. Kulkarni, Catherine L. Wang, Carolyn R. Bertozzi

Selected by 04 May 2020

Berrak Ugur

Neuroscience

ZeroCostDL4Mic: an open platform to simplify access and use of Deep-Learning in Microscopy

Lucas von Chamier, Johanna Jukkala, Christoph Spahn, et al.

Selected by 24 March 2020

Mariana De Niz

Bioinformatics

Differential regulation of lineage commitment in human and mouse primed pluripotent stem cells by NuRD

Ramy Ragheb, Sarah Gharbi, Julie Cramard, et al.

Selected by 24 February 2020

Gabriel Aughey

Developmental Biology

Fully Unsupervised Probabilistic noise2Void

Mangal Prakash, Manan Lalit, Pavel Tomancak, et al.

Selected by 11 January 2020

Mariana De Niz

Bioinformatics

Deep Learning-Based Point-Scanning Super-Resolution Imaging

Linjing Fang, Fred Monroe, Sammy Weiser Novak, et al.

Selected by 30 September 2019

Mariana De Niz

Bioinformatics

Multi-scale spatial heterogeneity enhances particle clearance in airway ciliary arrays

Guillermina R. Ramirez-San Juan, Arnold J. T. M. Mathijssen, Mu He, et al.

Selected by 29 July 2019

Mariana De Niz

Biophysics

A phylogenomic analysis of Nepenthes (Nepenthaceae)

Bruce Murphy, Félix Forest, Timothy Barraclough, et al.

Selected by 27 July 2019

Edi Sudianto

Evolutionary Biology