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Human pluripotent stem cell-derived macrophages modify development of human kidney organoids

Filipa M. Lopes, Ioannis Bantounas, Alexandra Sarov, et al.

Snake venom metalloproteinases are predominantly responsible for the cytotoxic effects of certain African viper venoms

Keirah E. Bartlett, Adam Westhorpe, Mark C. Wilkinson, et al.

Cryo-EM reveals multiple mechanisms of ribosome inhibition by doxycycline

William S. Stuart, Michail N. Isupov, Mathew McLaren, et al.

Taxane-Induced Conformational Changes in the Microtubule Lattice Activate GEF-H1-Dependent RhoA Signaling

Joyce C. M. Meiring, Varsha Mahapatra, Molly S.C. Gravett, et al.

Junctional Heterogeneity Shapes Epithelial Morphospace

Anubhav Prakash, Raman Kaushik, Nishant Singh, et al.

Mitochondrial Fatty Acid Oxidation is Stimulated by Red Light Irradiation

Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Mauricio S. Baptista, et al.

Discussion

Loss of MGST1 during fibroblast differentiation enhances vulnerability to oxidative stress in human heart failure

Mohamad Youness, Onne A.H.O. Ronda, Ankit Pradhan, et al.

Discussion

Imaging cellular activity simultaneously across all organs of a vertebrate reveals body-wide circuits

Virginia M. S. Ruetten, Wei Zheng, Igor Siwanowicz, et al.

Microbial Feast or Famine: dietary carbohydrate composition and gut microbiota metabolic function

Blake Dirks, Alex E. Mohr, Karen D. Corbin, et al.

Discussion

Scalable transcription factor mapping uncovers the regulatory dynamics of natural and synthetic transcription factors in human T cell states

Riley D.Z. Mullins, Jesse Zaretsky, Emily Stoller, et al.

Discussion

Vitamin B12 supports skeletal muscle oxidative phosphorylation capacity in male mice

Luisa F. Castillo, Katarina E. Heyden, Abigail R. Williamson, et al.

Discussion

A high-coverage genome from a 200,000-year-old Denisovan

Stéphane Peyrégne, Diyendo Massilani, Yaniv Swiel, et al.

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A global map for introgressed structural variation and selection in humans

PingHsun Hsieh, Natthapon Soisangwan, David S. Gordon, et al.

Discussion