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Evolution of mouse circadian enhancers from transposable elements

Julius Judd, Hayley Sanderson, Cédric Feschotte

Selected by Miguel V. Almeida

A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic Heart Disease

Michael Alexanian, Pawel F. Przytycki, Rudi Micheletti, et al.

Selected by Osvaldo Contreras, Alexander Ward

Guide RNA categorization enables target site choice in Tn7-CRISPR-Cas transposons

Michael T. Petassi, Shan-Chi Hsieh, Joseph E. Peters

Selected by haridha shivram

Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance

Ruben Schep, Eva Brinkman, Christ Leemans, et al.

Selected by Katie Weiner

Organoid Easytag: an efficient workflow for gene targeting in human organoids

Dawei Sun, Lewis D. Evans, Emma L. Rawlins

Selected by Kirsty Ferguson

A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues

Robert J. Nims, Lara Pferdehirt, Noelani B. Ho, et al.

Selected by Zhang-He Goh

Combinatorial patterns of graded RhoA activation and uniform F-actin depletion promote tissue curvature

Marlis Denk-Lobnig, Natalie C Heer, Adam C Martin

Selected by Grace Lim

Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens

Emanuel Gonçalves, Aldo Segura-Cabrera, Clare Pacini, et al.

Selected by Georgina Sava

Identification of neural oscillations and epileptiform changes in human brain organoids

Ranmal A. Samarasinghe, Osvaldo A. Miranda, Simon Mitchell, et al.

Selected by Theresa Pohlkamp

Stress Resets Transgenerational Small RNA Inheritance

Leah Houri-Ze’evi, Guy Teichman, Hila Gingold, et al.

Selected by Miguel V. Almeida

Human cardiac fibrosis-on-a-chip model recapitulates disease hallmarks and can serve as a platform for drug screening

Olya Mastikhina, Byeong-Ui Moon, Kenneth Williams, et al.

Selected by Hiroyoshi Y. Tanaka

Apicomplexan F-actin is required for efficient nuclear entry during host cell invasion

Mario Del Rosario, Javier Periz, Georgios Pavlou, et al.

Selected by Juan Quintana