Search results

High-throughput single-cell CRISPRi screens stratify neurodevelopmental functions of schizophrenia-associated genes

Umut Yildiz, Annique Claringbould, Mikael Marttinen, et al.

Selected by 27 October 2025

Manuel Lessi, Riccardo Nagni

Discussion

FUS Mislocalization Rewires a Cortical Gene Network to Drive 2 Cognitive and Behavioral Impairment in ALS

Raphaelle CASSEL, Félicie LORENC, Aurélie BOMBARDIER, et al.

Selected by 14 July 2025

Taylor Stolberg

Discussion

Identification of neuron-glia signaling feedback in human schizophrenia using patient-derived, mix-and-match forebrain assembloids

Eunjee Kim, Yunhee Kim, Soojung Hong, et al.

Selected by 12 June 2025

Justine Gromaire et al.

Discussion

Deletion of PIEZO1 in adult cardiomyocytes accelerates cardiac aging and causes premature death

Ze-Yan Yu, Yang Guo, Scott Kesteven, et al.

Selected by 17 March 2025

Theodora Stougiannou

Discussion

Triglyceride metabolism controls inflammation and APOE4-associated disease states in microglia

Roxan A. Stephenson, Kory R. Johnson, Linling Cheng, et al.

Selected by 22 August 2024

Gustavo Stelzer, Marcus Oliveira

LINC complex alterations are a hallmark of sporadic and familial ALS/FTD

Riccardo Sirtori, Michelle Gregoire, Emily Potts, et al.

Selected by 03 June 2024

Megane Rayer et al.

Feedback loop regulation between viperin and viral hemorrhagic septicemia virus through competing protein degradation pathways

Xiaobing Lu, Meisheng Yi, Zhe Hu, et al.

Selected by 21 May 2024

UofA IMB565 et al.

Discussion

PPARγ mediated enhanced lipid biogenesis fuels Mycobacterium tuberculosis growth in hepatocytes

Binayak Sarkar, Jyotsna Singh, Mohit Yadav, et al.

Selected by 14 May 2024

UofA IMB565 et al.

Discussion

Aspergillus dsRNA virus drives fungal fitness and pathogenicity in the mammalian host

Vanda Lerer, Marina Rocha, John Adeoye, et al.

Selected by 13 May 2024

UofA IMB565 et al.

Transcriptional profiling of human brain cortex identifies novel lncRNA-mediated networks dysregulated in amyotrophic lateral sclerosis

Alessandro Palma, Monica Ballarino

Selected by 16 April 2024

Julio Molina Pineda

Discussion

Spatial transcriptomics elucidates medulla niche supporting germinal center response in myasthenia gravis thymoma

Yoshiaki Yasumizu, Makoto Kinoshita, Martin Jinye Zhang, et al.

Selected by 27 March 2024

Jessica Chevallier

Discussion

Prenatal inflammation reprograms hyperactive ILC2s that promote allergic lung inflammation and airway dysfunction

Diego A. López, Aleah Griffin, Lorena Moreno Aguilar, et al.

Selected by 08 February 2024

Marina Schernthanner

Discussion