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Levetiracetam prevents Aβ42 production through SV2a-dependent modulation of App processing in Alzheimer’s disease models

Nalini R. Rao, Olivia DeGulis, Toshihiro Nomura, et al.

Factor XI localization in human deep venous thrombus and function of activated factor XI on venous thrombus formation and hemostasis in rabbit

Nobuyuki Oguri, Toshihiro Gi, Eriko Nakamura, et al.

Discussion

Alzheimer’s Disease Patient Brain Extracts Induce Multiple Pathologies in Vascularized Neuroimmune Organoids for Disease Modeling and Drug Discovery

Yanru Ji, Xiaoling Chen, Meek Connor Joseph, et al.

Modular control of time and space during vertebrate axis segmentation

Ali Seleit, Ian Brettell, Tomas Fitzgerald, et al.

AND

Natural genetic variation quantitatively regulates heart rate and dimension

Jakob Gierten, Bettina Welz, Tomas Fitzgerald, et al.

14-3-3 binding regulates Tau assembly and microtubule association

Janine Hochmair, Maxime C. M. van den Oetelaar, Lisa Diez, et al.

Discussion

Prenatal inflammation reprograms hyperactive ILC2s that promote allergic lung inflammation and airway dysfunction

Diego A. López, Aleah Griffin, Lorena Moreno Aguilar, et al.

Discussion

TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling

Luyang Xiong, Irina Zhevlakova, Xiaoxia Z. West, et al.

Hypoxia blunts angiogenic signaling and upregulates the antioxidant system in elephant seal endothelial cells

Kaitlin N Allen, Julia María Torres-Velarde, Juan Manuel Vazquez, et al.

CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

Avi J. Samelson, Nabeela Ariqat, Justin McKetney, et al.

Discussion

Mitochondrial citrate carrier SLC25A1 is a dosage-dependent regulator of metabolic reprogramming and morphogenesis in the developing heart

Chiemela Ohanele, Jessica N. Peoples, Anja Karlstaedt, et al.

Discussion

A Single Laccase Acts as a Key Component of Environmental Sensing in a Broad Host Range Fungal Pathogen

Nathaniel M. Westrick, Eddie G. Dominguez, Christina M. Hull, et al.

Discussion

A data-driven Boolean model explains memory subsets and evolution in CD8+ T cell exhaustion

Geena V. Ildefonso, Stacey D. Finley