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A data-driven Boolean model explains memory subsets and evolution in CD8+ T cell exhaustion

Geena V. Ildefonso, Stacey D. Finley

Selected by 10 April 2023

Benjamin Dominik Maier

Systems Biology

Insm1 regulates the development of mTECs and immune tolerance

Wehuai Tao, Yiqiu Wei, Zhihuan Ye, et al.

Selected by 28 February 2023

Marina Schernthanner, Jessica Chevallier

Bioinformatics

peer review in Biomedical Sciences

Communication of scientific knowledge has changed dramatically in recent decades and the public perception of scientific discoveries depends on the peer review process of articles published in scientific journals. Preprints are key vehicles for the dissemination of scientific discoveries, but they are still not properly recognized by the scientific community since peer review is very limited. On the other hand, peer review is very heterogeneous and a fundamental aspect to improve it is to train young scientists on how to think critically and how to evaluate scientific knowledge in a professional way. Thus, this course aims to: i) train students on how to perform peer review of scientific manuscripts in a professional manner; ii) develop students' critical thinking; iii) contribute to the appreciation of preprints as important vehicles for the dissemination of scientific knowledge without restrictions; iv) contribute to the development of students' curricula, as their opinions will be published and indexed on the preLights platform. The evaluations will be based on qualitative analyses of the oral presentations of preprints in the field of biomedical sciences deposited in the bioRxiv server, of the critical reports written by the students, as well as of the participation of the students during the preprints discussions.

 



List by Marcus Oliveira et al.

3D genome organization around nuclear speckles drives mRNA splicing efficiency

Prashant Bhat, Amy Chow, Benjamin Emert, et al.

Selected by 16 February 2023

Diego Martínez

Cell Biology

Preprint peer review enhances undergraduate biology students’ disciplinary literacy and sense of belonging in STEM

Josie L. Otto, Gary S McDowell, Meena M. Balgopal, et al.

Selected by 14 December 2022

Reinier Prosee et al.

Scientific Communication and Education

mTORC1 is required for differentiation of germline stem cells in the Drosophila melanogaster testis

Marie Clémot, Cecilia D’Alterio, Alexa Kwang, et al.

Selected by 28 November 2022

Diego Sainz de la Maza

Cell Biology

Intestinal lamina propria supports acquired eTreg suppressor function

Yisu Gu, Raquel Bartolomé-Casado, Chuan Xu, et al.

Selected by 03 November 2022

Marina Schernthanner

Immunology

Addressing structural mentoring barriers in postdoctoral training: A qualitative study

W. Marcus Lambert, Nanda Nana, Suwaiba Afonja, et al.

Selected by 21 September 2022

Reinier Prosee et al.

Scientific Communication and Education

Disrupting cellular memory to overcome drug resistance

Guillaume Harmange, Raúl A. Reyes Hueros, Dylan Schaff, et al.

Selected by 18 September 2022

Nate Mullin

Cell Biology

Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart

Gianluca Amadei, Charlotte E Handford, Joachim De Jonghe, et al.

AND

Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development

Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, et al.

Selected by 05 September 2022

Monica Tambalo et al.

Cell Biology

The ELT-3 GATA factor specifies endoderm in Caenorhabditis angaria in an ancestral gene network

Gina Broitman-Maduro, Morris F. Maduro

Selected by 11 June 2022

Chee Kiang Ewe

Developmental Biology

Synthetic memory circuits for programmable cell reconfiguration in plants

James P B Lloyd, Florence Ly, Patrick Gong, et al.

AND

Synthetic genetic circuits enable reprogramming of plant roots

Jennifer A. N. Brophy, Katie J. Magallon, Kiril Kniazev, et al.

Selected by 28 April 2022

Gwendolyn K. Kirschner

Plant Biology