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Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies

Candice Gurbatri, Courtney Coker, Taylor E. Hinchliffe, et al.

AND

Programmable bacteria induce durable tumor regression and systemic antitumor immunity

Sreyan Chowdhury, Taylor E Hinchliffe, Samuel Castro, et al.

Discussion

Human DNA-PK activates a STING-independent DNA sensing pathway

Katelyn Burleigh, Joanna H. Maltbaek, Stephanie Cambier, et al.

Discussion

A Bile Duct-on-a-Chip with Organ-Level Functions

Yu Du, Gauri Khandekar, Jessica Llewellyn, et al.

Blue light induces neuronal-activity-regulated gene expression in the absence of optogenetic proteins

Kelsey M. Tyssowski, Jesse M. Gray

Discussion

Optical determination of absolute membrane potential

Julia R. Lazzari-Dean, Anneliese M.M. Gest, Evan Miller

Discussion

Hepatocyte-specific deletion of Pparα promotes NASH in the context of obesity

Marion Regnier, Arnaud Polizzi, Sarra Smati, et al.

Establishment of the mayfly Cloeon dipterum as a new model system to investigate insect evolution

Isabel Almudi, Carlos Martin-Blanco, Isabel Maria Garcia-Fernandez, et al.

Regulation of modulatory cell activity across olfactory structures in Drosophila melanogaster

Xiaonan Zhang, Kaylynn Coates, Andrew Dacks, et al.

A direct and widespread role for the nuclear receptor EcR in mediating the response to ecdysone in Drosophila

Christopher M Uyehara, Daniel J McKay

Discussion

Single cell RNA-Seq reveals distinct stem cell populations that drive sensory hair cell regeneration in response to loss of Fgf and Notch signaling

Mark E. Lush, Daniel C. Diaz, Nina Koenecke, et al.

AND

Distinct progenitor populations mediate regeneration in the zebrafish lateral line.

Eric D Thomas, David Raible

Unlimited genetic switches for cell-type specific manipulation

Jorge Garcia-Marques, Ching-Po Yang, Isabel Espinosa-Medina, et al.

Reduced mitochondrial lipid oxidation leads to fat accumulation in myosteatosis

Jonathan P Gumucio, Austin H Qasawa, Patrick J Ferrara, et al.

Discussion