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Excitable Rho dynamics drive cell contractions by sequentially inducing ERM protein-mediated actin-membrane attachment and actomyosin contractility

Seph Marshall-Burghardt, Rodrigo A. Migueles-Ramírez, Qiyao Lin, et al.

Inferring protein from mRNA concentrations using convolutional neural networks

Patrick Maximilian Schwehn, Pascal Falter-Braun

Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair

Marieke R. Wensveen, Aditya A. Dixit, Serafin U. Colmenares, et al.

Characterization of Identified Dopaminergic Neurons in the Mouse Forebrain and Midbrain

Maggy Yu Hei Lau, Sana Gadiwalla , Susan Jones, et al.

Structured RhoGEF recruitment drives myosin ii organization on large exocytotic vesicles

Kumari Kamalesh, Dagan Segal, Ori Avinoam, et al.

Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions

Mrityunjoy Kar, Laura T. Vogel, Gaurav Chauhan, et al.

Discussion

Caveola mechanotransduction reinforces the cortical cytoskeleton to promote epithelial resilience

John W. Brooks, Vikas Tillu, Suzie Verma, et al.

Atlas of Plasmodium falciparum intraerythrocytic development using expansion microscopy

Benjamin Liffner, Ana Karla Cepeda Diaz, James Blauwkamp, et al.

SQ3370, the first clinical click chemistry-activated cancer therapeutic, shows safety in humans and translatability across species

Sangeetha Srinivasan, Nathan A. Yee, Michael Zakharian, et al.

Cell polarity linked to gravity sensing is generated by protein translocation from statoliths to the plasma membrane

Takeshi Nishimura, Shogo Mori, Hiromasa Shikata, et al.

AND

Amyloplast sedimentation repolarizes LAZYs to achieve gravity sensing in plants

Jiayue Chen, Renbo Yu, Na Li, et al.

Inhibition of Centrosome Clustering Reduces Cystogenesis and Improves Kidney Function in Autosomal Dominant polycystic Kidney Disease

Tao Cheng, Aruljothi Mariappan, Ewa Langner, et al.

3D genome organization around nuclear speckles drives mRNA splicing efficiency

Prashant Bhat, Amy Chow, Benjamin Emert, et al.