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OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide

Hugo Sepulveda, Xiang Li, Xiaojing Yue, et al.

Selected by 17 April 2024

Mansi

Developmental Biology

An epigenetic barrier sets the timing of human neuronal maturation

Gabriele Ciceri, Hyunwoo Cho, Meghana Kshirsagar, et al.

Selected by 01 December 2022

PiCLS Dundee

Neuroscience

Diverse mechanisms for epigenetic imprinting in mammals

Daniel Andergassen, Zachary D. Smith, John L. Rinn, et al.

Selected by 18 June 2021

Sergio Menchero

Genetics

The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo

Giuliano Crispatzu, Rizwan Rehimi, Tomas Pachano, et al.

Selected by 17 February 2021

Sergio Menchero

Molecular Biology

Orphan CpG islands boost the regulatory activity of poised enhancers and dictate the responsiveness of their target genes

Tomás Pachano, Víctor Sánchez-Gaya, María Mariner-Faulí, et al.

Selected by 07 September 2020

Jesus Victorino

Genetics

The deubiquitinase Usp9x regulates prc2-mediated chromatin reprogramming during mouse development

Trisha A. Macrae, Miguel Ramalho-Santos

Selected by 07 August 2020

Sergio Menchero

Molecular Biology

Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics

S Basu, O Shukron, A Ponjavic, et al.

AND

Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy

Miles K. Huseyin, Robert J. Klose

Selected by 22 May 2020

Gabriel Aughey

Maintenance of spatial gene expression by Polycomb-mediated repression after formation of a vertebrate body plan

Julien Rougot, Naomi D Chrispijn, Marco Aben, et al.

Selected by 07 January 2019

Yen-Chung Chen

Cell Biology

Capturing the onset of prc2-mediated repressive domain formation

Ozgur Oksuz, Varun Narendra, Chul-Hwan Lee, et al.

Selected by 31 March 2018

Boyan Bonev

Genomics
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